Preference for Human Papillomavirus Self-Collection and Papanicolaou: Survey of Underscreened Women in North Carolina.
Preference for Human Papillomavirus Self-Collection and Papanicolaou: Survey of Underscreened Women in North Carolina.
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DOI：
10.1097/lgt.0000000000000430
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发表时间：
2018-10
影响因子：
3.7
通讯作者：
Smith JS
中科院分区：
文献类型：
--
作者：
Kilfoyle KA;Des Marais AC;Ngo MA;Romocki L;Richman AR;Barclay L;Brewer NT;Rahangdale L;Smith JS
自我采集人类乳头瘤病毒(HPV)检测样本(自我采集)有可能增加筛查不足的妇女中的宫颈癌筛查。我们评估了这些高危人群对家庭HPV自我采集与基于诊所的巴氏杆菌检测的态度。参与者是北卡罗来纳州的低收入女性，早该进行宫颈癌筛查。妇女在家中自行采集样本，邮寄样本进行HPV检测，并填写家庭HPV自我采集电话问卷。参与者被转介到以诊所为基础的巴氏检测，并被邀请完成关于巴氏检测的第二份问卷。横断面问卷比较了自我采集与巴氏涂片检测的态度、经历和偏好，并评估了HPV自我采集偏好的预测因素。在221名女性中，一半(51%)报告倾向于HPV自我收集，19%倾向于巴氏试验，27%报告没有偏好。更多的女性表示很难抽出时间做巴氏测试(31%)而不是自我测试(13%，p=0.003)，更多的女性对自我测试结果感到害怕(50%)而不是巴氏测试结果(36%)(p=0.02)。自我收集的身体不适和疼痛的报告相对较少(不适感：18%自我；48%自我；疼痛：8%自我；30%自我，p=0.001)。在对测试的正面和负面想法、对测试的安全性和准确性的信任以及是否愿意再次进行测试方面，没有发现差异。总体而言，在筛查不足的妇女中，与巴氏检测相比，对HPV自我收集的积极态度表明，在这一高危人群中，自我收集是一个有希望的选择，可以增加宫颈癌筛查。
Self-collection of samples for human papillomavirus (HPV) testing (self-collection) has the potential to increase cervical cancer screening among underscreened women. We assessed attitudes towards at-home HPV self-collection compared to clinic-based Pap testing in this higher risk population. Participants were low-income, women in North Carolina overdue for cervical cancer screening. Women self-collected samples at home, returned samples by mail for HPV testing, and completed phone questionnaires about at-home HPV self-collection. Participants were referred to clinic-based Pap testing and invited to complete a second questionnaire about Pap testing. A cross-sectional questionnaire compared attitudes, experiences, and preferences for self-collection versus Pap testing, and assessed predictors of preference for HPV self-collection. Half (51%) of 221 women reported a preference for HPV self-collection, 19% preferred Pap testing, and 27% reported no preference. More women reported finding difficulty finding time to do the Pap test (31%) than the self-test (13%, p=0.003), and being afraid of the self-test results (50%) than the Pap test results (36%, p=0.02). There were relatively fewer reports of physical discomfort and pain from self-collection than Pap testing (discomfort: 18% self; 48% Pap; pain: 8% self; 30% Pap, p=0.001). No differences were found in positive versus negative thoughts about the tests, trust in the tests’ safety and accuracy, or willingness to do tests again. Overall positive attitudes towards HPV self-collection compared to Pap testing among underscreened women suggest that self-collection is a promising option to increase cervical cancer screening in this high-risk population.