Endothelial keratoplasty - A simplified technique to minimize graft dislocation, iatrogenic graft failure, and pupillary block
Endothelial keratoplasty - A simplified technique to minimize graft dislocation, iatrogenic graft failure, and pupillary block
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DOI：
10.1016/j.ophtha.2007.09.005
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发表时间：
2008-07-01
期刊：
影响因子：
13.7
通讯作者：
Friend, Daniel J.
中科院分区：
文献类型：
--
作者：
Terry, Mark A.;Shamie, Neda;Friend, Daniel J.
目的：内皮角膜移植是替代全层穿透性角膜移植的一种令人兴奋的替代方法，但主要的并发症有供体组织脱位、一期植片失败(PGF)和瞳孔堵塞残留的支持性气泡。在我们连续200例Descemet剥离自动内皮角膜移植(DSAEK)的病例中，我们制定了手术策略以减少这些并发症的发生。设计：前瞻性、非对比、干预性病例系列。参与者：172名角膜水肿症患者的200只眼。方法：启动一项机构审查委员会批准的前瞻性内皮角膜移植方案。四位不同的外科医生对最初的200例连续进行了DSAEK，使用了一种外周受者床刮取供体边缘粘连的技术，并留下了可以自由移动的残余支持性气泡，以及
Purpose: Endothelial keratoplasty is an exciting alternative to full-thickness penetrating keratoplasty for replacing the diseased endothelium, yet 3 of the major complications seen are dislocation of the donor tissue, primary graft failure (PGF), and pupillary block from the residual, supportive air bubble. Surgical strategies were developed to reduce the likelihood of occurrence of these complications in our first 200 consecutive Descemet's stripping automated endothelial keratoplasty (DSAEK) cases.Design: Prospective, noncomparative, interventional case series.Participants: Two hundred eyes of 172 patients with corneal edema.Methods: An institutional review board-approved, prospective protocol of endothelial keratoplasty was initiated. Four different surgeons performed DSAEK for the initial 200 consecutive cases using a technique of peripheral recipient bed scraping for donor edge adherence and leaving a residual supportive air bubble, which was freely mobile, and