Agreement between capillary and arterial lactate in the newborn
Agreement between capillary and arterial lactate in the newborn
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DOI：
10.1080/080352502753458003
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发表时间：
2002-01-01
期刊：
影响因子：
3.8
通讯作者：
Bucher, HU
中科院分区：
文献类型：
--
作者：
Fauchère, JC;Bauschatz, AS;Bucher, HU
动脉血乳酸是反映组织氧债的可靠指标，对各种疾病引起的循环衰竭的程度和预后有一定的参考价值。因此，在新生儿中研究了毛细血管乳酸盐测量是否具有同等价值的实际问题。总共有193个毛细血管和动脉血乳酸浓度的同时测量进行了25个新生儿留置脐动脉导管。毛细血管和动脉乳酸浓度之间存在强线性相关性（L-cap = 1.02 L-art + 0.04：r = 0.98; p < 0.001）。平均差异为-0.08 mmol/l，一致性限（+/- 2 SD）为+/- 0.69 mmol/l（-0.77至0.61 mmol/l）。结论：我们的数据表明，新生儿毛细血管血乳酸测量产生的乳酸浓度在很大的浓度范围内相当于动脉测量。
Arterial blood lactate is a reliable indicator of tissue oxygen debt and is of value in expressing the degree and prognosis of circulatory failure as a result of various diseases. Therefore, the practical issue of whether capillary lactate measurements might be of equal value was investigated in newborns. In total, 193 simultaneous measurements of capillary and arterial blood lactate concentrations were performed in 25 newborn babies with an indwelling umbilical arterial catheter. A strong linear correlation was found between capillary and arterial lactate concentration (L-cap = 1.02 L-art + 0.04: r = 0.98; p < 0.001). The mean difference was -0.08 mmol/l and the limits of agreement (+/- 2 SD) were +/- 0.69 mmol/l (-0.77 to 0.61 mmol/l).Conclusion: Our data show that capillary blood lactate measurements in newborn babies yield lactate concentrations equivalent to arterial measurements over a large concentration range.