The prevalence of aortic calcification in Japanese compared to white and Japanese-American middle-aged men is confounded by the amount of cigarette smoking
The prevalence of aortic calcification in Japanese compared to white and Japanese-American middle-aged men is confounded by the amount of cigarette smoking
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DOI：
10.1016/j.ijcard.2011.12.060
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发表时间：
2013-07-15
影响因子：
3.5
通讯作者：
Sekikawa, Akira
中科院分区：
文献类型：
--
作者：
El-Saed, Aiman;Curb, J. David;Sekikawa, Akira
背景：日本男性冠状动脉钙化（CAC）的患病率低于白人和日裔美国男性。目前尚不清楚与吸烟密切相关的主动脉钙化（AC）在日本男性中是否也较低，日本男性的吸烟率是美国男性的许多倍。方法：我们进行了一项以人群为基础的研究，随机选择903名年龄在40-49岁之间的男性：310名日本Kusatsu男性，301名美国Allegheny县白人男性，292名美国夏威夷男性（2002-2006）。通过电子束断层扫描评估AC的存在。AC定义为Agatston主动脉钙评分(AoCaS) >, >= 100。结果：日本人（35.8%）的AoCaS水平明显低于两种白人(68.8%,p
Background: The prevalence of coronary artery calcification (CAC) in Japanese men is lower than in white and Japanese-American men. It is unclear if aortic calcification (AC) strongly linked to smoking is also lower in Japanese men who have many times higher smoking prevalence compared to US men.Methods: We conducted a population-based study of 903 randomly-selected men aged 40-49 years: 310 Japanese men in Kusatsu, Japan, 301 white men in Allegheny County, US, and 292 Japanese men in Hawaii, US (2002-2006). The presence of AC was assessed by electron-beam tomography. AC was defined as Agatston aortic calcium scores (AoCaS) > 0 and >= 100.Results: Japanese (35.8%) had significantly less AoCaS>0 compared to both white (68.8%, p