Healthcare workers and H1N1 vaccination: Does having a chronic disease make a difference?
Healthcare workers and H1N1 vaccination: Does having a chronic disease make a difference?
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DOI：
10.1016/j.vaccine.2011.12.037
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发表时间：
2012-02-01
期刊：
影响因子：
5.5
通讯作者：
Tang, Wern Ee
中科院分区：
文献类型：
--
作者：
Toh, Matthias Paul Han Sim;Kannan, Predeebha;Tang, Wern Ee
为应对2009年的大流行，研制了一种新型甲型h1n1流感疫苗。本研究描述了初级卫生保健诊所中有或没有慢性疾病的卫生保健工作者（HCWs）接种H1N1疫苗的意愿，他们拒绝接种疫苗的原因，以及他们是否寻求额外信息以做出接种疫苗的知情决定。材料和方法：2009年11月在新加坡9个初级保健诊所的所有医疗、护理、联合保健和业务卫生保健员中进行了一项匿名调查。参与者被问及是否患有任何与流感相关的并发症相关的慢性疾病（例如：哮喘、中风、心脏病、癌症、糖尿病、肾病），以及他们在过去两年内对接种H1N1疫苗和季节性流感疫苗的看法。结果：初步回复率为80%，共分析完成问卷711份（54.7%）。在711名受访者中，16.6%的人报告至少患有一种慢性病。哮喘（10.8%）、高血压（10.4%）和血脂异常（9.8%）是主要的慢性疾病。只有39.4%的受访者愿意接种甲型h1n1流感疫苗。男性接种HI - NI疫苗的可能性是女性的2.07倍（95% CI 1.19-3.62）；45-54岁和55岁以上患者的意愿分别是25岁以下患者的2.12倍（95% CI 1.06-4.24）和2.44倍（95% CI 1.13-5.27）；考虑接受季节性流感疫苗的人比不接受的人多7.0倍（95%Cl 4.48-10.92）。两个主要障碍是“对副作用的恐惧”和“不确定疫苗的有效性”。虽然78%的人参加了一些与h1 - 1相关的讲座，但只有7%的卫生保健工作者认为他们获得了足够的信息。大多数人想要更多关于疫苗安全性和禁忌症的信息。结论：不到40%的卫生保健工作者表示愿意接种H1N1疫苗，低于过去的流感疫苗接种率。在初级保健诊所有慢性疾病的卫生保健工作者并不认为自己有更高的发生H1N1相关并发症的风险，也不比其他卫生保健工作者更愿意接受H1N1疫苗接种。疫苗的副作用和有效性是主要问题。有针对性的健康信息涵盖了疫苗的安全性，可能会提高H1N1疫苗的使用率。(C) 2011 Elsevier Ltd.版权所有。
Introduction: A novel HIN1 vaccine was manufactured in response to the pandemic in 2009. This study describes the willingness to be vaccinated for H1N1 among healthcare workers (HCWs) in primary healthcare clinics with and without chronic medical conditions, their reasons for refusing vaccination and whether they sought additional information to make an informed decision for the vaccination.Materials and methods: An anonymous survey was conducted in November 2009 among all medical, nursing, allied health and operations HCWs in nine primary care clinics in Singapore. Participants were asked if they had any chronic medical conditions associated with influenza-related complications (example: asthma, stroke, heart disease, cancer, diabetes mellitus, renal disease), their perception towards vaccination for H1N1 and against seasonal influenza within the preceding 2 years.Results: The initial response rate was 80%, of which 711(54.7%) of the completed surveys were analysed. Among the 711 respondents, 16.6% reported having at least 1 chronic disease. Asthma (10.8%), hypertension (10.4%) and dyslipidaemia (9.8%) were the main chronic conditions. Only 39.4% of respondents were willing to be vaccinated against H1 N1. Males were 2.07 (95% CI 1.19-3.62) times more likely than females to receive the HI NI vaccination; the 45-54 and 55+ years old were 2.12 (95% CI 1.06-4.24) and 2.44 (95% CI 1.13-5.27) times more willing than those below 25 years old; and those who considered accepting the seasonal influenza vaccine were 7.0 times more likely than those who did not (95%Cl 4.48-10.92).The 2 principal barriers were "fear of side effects" and "unsure of vaccine's effectiveness". Although 78% attended some H1N1-related talks, only 7% of all HCWs felt that they had sufficient information. Most wanted more information about the vaccine's safety profile and contraindications.Conclusion: Fewer than 40% of HCWs expressed willingness to receive the H1N1 vaccination, lower than past rates of influenza vaccine. HCWs in primary care clinics who had a chronic condition did not perceive themselves to be at higher risk of developing H1N1-related complications and were not more willing than the rest of the HCWs to accept H1N1 vaccination. Vaccine's side effects and effectiveness were the main concerns. Uptake of H1N1 vaccine may improve with targeted health information covering the vaccine's safety profile. (C) 2011 Elsevier Ltd. All rights reserved.