The relation of overweight to cardiovascular risk factors among children and adolescents: The Bogalusa heart study

The relation of overweight to cardiovascular risk factors among children and adolescents: The Bogalusa heart study
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DOI:
10.1542/peds.103.6.1175
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发表时间:
1999-06-01
期刊:
影响因子:
8
通讯作者:
Berenson, GS
Berenson, GS
中科院分区:
医学2区
文献类型:
--
作者:
Freedman, DS;Dietz, WH;Berenson, GS

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背景虽然儿童期超重和肥胖与血脂异常、高胰岛素血症和高血压有关,但大多数研究都单独检查了这些风险因素的水平,或使用内部分界点(如五分位数)对超重和风险因素进行分类。我们使用从几项国家研究中得出的临界点来检查超重(克托莱指数,>第95百分位数)与不利危险因素水平和危险因素聚集的关系。样本包括1973年至1994年由博加卢萨心脏研究所进行的7项横断面研究中的9167名5- 17岁儿童。大约11%的受检学童被认为超重。虽然不良血脂,胰岛素和血压水平没有显着变化与克托莱指数水平
Background. Although overweight and obesity in childhood are related to dyslipidemia, hyperinsulinemia, and hypertension, most studies have examined levels of these risk factors individually or have used internal cutpoints (eg, quintiles) to classify overweight and risk factors.Objective. We used cutpoints derived from several national studies to examine the relation of overweight (Quetelet index, >95th percentile) to adverse risk factor levels and risk factor clustering.Design. The sample consisted of 9167 5- to 17-year-olds examined in seven cross-sectional studies conducted by the Bogalusa Heart Study between 1973 and 1994.Results. About 11% of examined schoolchildren were considered overweight. Although adverse lipid, insulin, and blood pressure levels did not vary substantially with the Quetelet index at levels