An efficient method in stannylcupration of a methyl substituted enyne or alkyne by kinetic control using methanol
An efficient method in stannylcupration of a methyl substituted enyne or alkyne by kinetic control using methanol
复制标题
DOI：
10.1016/s0040-4039(97)00361-4
复制
发表时间：
1997-03-31
影响因子：
1.8
通讯作者：
Pancrazi, A
中科院分区：
文献类型：
--
作者：
Betzer, JF;Ardisson, J;Pancrazi, A
用高甲锡烷基铜酸盐（Bu（3）Sn）（2）CuCNLi 2进行烯炔5的甲锡基铜化，以立体选择性方式以77%的产率递送远端二烯基锡烷7。该反应只有在向铜酸盐溶液中加入甲醇时才可重现。相比之下，硼氢化或锆氢化反应在这种情况下未能产生相应的硼或锆衍生物，（C）1997 Elsevier Science Ltd.
Stannylcupration of enyne 5 was performed with the homostannylcuprate (Bu(3)Sn)(2)CuCNLi2 to deliver in a stereoselective way the distal dienylstannane 7 in 77% yield. This reaction was reproducible only when methanol was added to the cuprate solution. In comparison, hydroboration or hydrozirconation reactions failed in this case to produce the corresponding boron or zirconium derivative, (C) 1997 Elsevier Science Ltd.