Incidence of diabetes in Asian-Indian subjects: A five year follow-up study from Bangladesh
Incidence of diabetes in Asian-Indian subjects: A five year follow-up study from Bangladesh
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DOI：
10.1016/j.pcd.2011.01.002
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发表时间：
2011-07-01
影响因子：
2.9
通讯作者：
Hussain, Akhtar
中科院分区：
文献类型：
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作者：
Asghar, Shaheen;Khan, Abul Kalam Azad;Hussain, Akhtar
目的：了解2型糖尿病的发病率及其危险因素。进一步研究肥胖（BMI和腰围）相对变化的影响。方法：随机抽取2011名20岁及以上非糖尿病成年人，随访时间为1999年至2004年。空腹血糖，包括生物物理和人体测量measured.Results：糖尿病的总体5年累积发病率为16.4每1000人年和65.1每1000人年的空腹血糖受损调整年龄和性别。在肥胖的措施，只有腰围>85英寸。增加男性糖尿病的风险（RR = 3.0）。对于男性，相对于基线值，BMI和WC降低>= 5%或BMI增加>15%的相对变化与糖尿病的偶发病例显著相关。增加男性的臀围与保护作用显着相关，而相反的协会被观察到为women.Conclusion：相对变化的损失和过度获得的BMI增加糖尿病的风险。对空腹血糖受损者进行针对性干预，可减少偶发病例。在亚洲印度受试者中，需要进一步研究非肥胖相关的糖尿病。(C)2011年欧洲糖尿病初级保健。由爱思唯尔有限公司出版。保留所有权利。
Aims: To determine the incidence of Type 2 diabetes and its risk factors. Further, to examine the effect of relative changes in obesity (BMI and waist circumference).Methods:A sample of 2011 non-diabetic adults aged 20 and above were randomly selected and followed from 1999 to 2004. Fasting blood glucose including biophysical and anthropometric measures was measured.Results: The overall 5 year cumulative incidence of diabetes was 16.4 per 1000 person-years and 65.1 per 1000 person-years in those with impaired fasting glucose adjusted for age and sex. Among obesity measures, only waist >85 in. increased the risk for diabetes in males (RR = 3.0). Relative changes stratified by loss in BMI and WC >= 5% or gain of BMI >15% from the baseline values for men were significantly associated with the incidental cases of diabetes. Increased hip circumference for men was significantly associated with a protective effect while an opposite association was observed for women.Conclusion: Relative change in both loss and excessive gain of BMI were risks for increased diabetes. Targeted intervention in those with impaired fasting blood glucose will expectedly reduce the incidental cases. Further investigations are needed for non obese related diabetes in Asian Indian subjects. (C) 2011 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.