Hip chondrolabral mechanics during activities of daily living: Role of the labrum and interstitial fluid pressurization.
Hip chondrolabral mechanics during activities of daily living: Role of the labrum and interstitial fluid pressurization.
复制标题
日常生活活动中的髋关节软骨盂力学：盂唇和间质液加压的作用。
DOI：
10.1016/j.jbiomech.2018.01.001
复制
发表时间：
2018
影响因子：
2.4
通讯作者：
Weiss,JeffreyA
中科院分区：
文献类型：
--
作者：
Todd,JocelynN;Maak,TravisG;Ateshian,GerardA;Maas,SteveA;Weiss,JeffreyA
髋部骨关节炎可以由力学因素引起，可以用有限元分析来研究。髋关节的有限元研究通常假设在模拟活动中关节软骨中没有明显的流体加压损失，并将材料近似为不可压缩和弹性。本研究考察了在生理运动期间间质液体负载支持维持的条件，以及唇状面在维持液体负载支持中的作用及其对周围软骨固相的影响。我们发现步态和下蹲的动态运动在周期之间保持了一致的流体负荷支持，而静态单腿站立经历了轻微的流体减压，显著减少了固相应力和应变。阴唇的存在对关节软骨内的流体负载支持没有显著影响，但防止了软骨边缘的变形，从而降低了软骨内的应力和应变条件。通过关节软骨厚度对胶原纤维方向的形态学准确表征对于预测液体负荷支持是不必要的。然而，与简化纤维增强的比较强调了生理上的重要性。本研究结果表明，弹性不可压缩材料近似可以合理地模拟有限数量的步态和下蹲循环运动，而不会显著降低准确性，但不适用于静态运动或大量重复运动。此外，在唇部修复的背景下，去除唇唇所看到的效果激发了对唇部再植策略的评估。
Osteoarthritis of the hip can result from mechanical factors, which can be studied using finite element (FE) analysis. FE studies of the hip often assume there is no significant loss of fluid pressurization in the articular cartilage during simulated activities and approximate the material as incompressible and elastic. This study examined the conditions under which interstitial fluid load support remains sustained during physiological motions, as well as the role of the labrum in maintaining fluid load support and the effect of its presence on the solid phase of the surrounding cartilage. We found that dynamic motions of gait and squatting maintained consistent fluid load support between cycles, while static single-leg stance experienced slight fluid depressurization with significant reduction of solid phase stress and strain. Presence of the labrum did not significantly influence fluid load support within the articular cartilage, but prevented deformation at the cartilage edge, leading to lower stress and strain conditions in the cartilage. A morphologically accurate representation of collagen fibril orientation through the thickness of the articular cartilage was not necessary to predict fluid load support. However, comparison with simplified fibril reinforcement underscored the physiological importance. The results of this study demonstrate that an elastic incompressible material approximation is reasonable for modeling a limited number of cyclic motions of gait and squatting without significant loss of accuracy, but is not appropriate for static motions or numerous repeated motions. Additionally, effects seen from removal of the labrum motivate evaluation of labral reattachment strategies in the context of labral repair.