The association between physical fitness and cardiovascular disease risk factors in children in a five-year follow-up study.
The association between physical fitness and cardiovascular disease risk factors in children in a five-year follow-up study.
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一项五年随访研究中儿童体质与心血管疾病危险因素之间的关联。
DOI：
10.1093/ije/18.4.830
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发表时间：
1989
影响因子：
7.7
通讯作者：
Walter,HJ
中科院分区：
文献类型：
--
作者：
Hofman,A;Walter,HJ
Hofman A（伊拉斯谟大学医学院流行病学系，邮政信箱1738，3000 DR鹿特丹，荷兰）和Walter HJ。对纽约37所小学所有四年级的633名儿童进行了体质与心血管疾病（CVD）危险因素之间关系的研究。他们参加了一项干预研究的对照组，以减少儿童心血管疾病的危险因素。在五年的随访期间，在基线和随后的四次检查中测量血压、总胆固醇和高密度脂蛋白（HDL）胆固醇以及身体健康。基线时收缩压（SBP）在体能差的儿童中最高。五年的体能变化与SBP的变化呈负相关，即体能下降最严重的儿童SBP上升幅度最大。在基线时，身体素质差的男孩的高密度脂蛋白胆固醇最低。五年的体能变化与男孩HDL胆固醇水平的变化呈正相关;即体能下降最大的男孩HDL胆固醇水平下降最大。这些观察结果表明，儿童期身体状况的不利长期变化可能与血压和血脂的不利变化有关。
Hofman A (Department of Epidemiology, Erasmus University Medical School, PO Box 1738, 3000 DR Rotterdam, The Netherlands) and Walter HJ. The association between physical fitness and cardiovascular disease risk factors in children in a five-year follow-up study.International Journal of Epidemiology1989,18: 830–835.The relation between physical fitness and cardiovascular disease (CVD) risk factors was studied in 633 children selected from all fourth grades in 37 elementary schools in New York. They were participating in the control group of an intervention study to reduce CVD risk factors in children. Blood pressure, total and high-density lipoprotein (HDL) cholesterol and physical fitness were measured at baseline and at four subsequent examinations during five years of follow-up. Systolic blood pressure (SBP) at baseline was highest in children with poor physical fitness. The five-year change in physical fitness was inversely associated with the change in SBP, ie, children with the strongest decline in physical fitness showed the largest rise in SBP. HDL cholesterol at baseline was lowest in boys with poor physical fitness. The five-year change in physical fitness was positively related to the change in HDL cholesterol levels in boys; ie, boys with the largest decline in physical fitness had the largest decrease in HDL cholesterol level. These observations indicate that unfavourable long-term changes in physical condition in childhood may be related to unfavourable changes in blood pressure and serum lipids.