Symptoms before and after surgery for colorectal cancer
Symptoms before and after surgery for colorectal cancer
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结直肠癌手术前后的症状
DOI：
10.1023/a:1026469512578
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发表时间：
2004
影响因子：
3.5
通讯作者：
A. Neilson
中科院分区：
文献类型：
--
作者：
D. Whynes;A. Neilson
调查问卷由患者样本（n=53）在结直肠癌手术前和手术后三个月的两个时间点完成。调查问卷包括作为一般健康状况衡量标准的诺丁汉健康概况以及包含 30 种症状的具体清单。在身体症状中，食欲不振、直肠出血和排便急迫感在治疗后似乎有所减轻，而其他潜在症状，例如呕吐，在手术前后似乎很少出现。治疗前的心理困扰症状似乎在三个月后就消失了，这表明这些症状更有可能是由于对治疗的预期而不是疾病本身造成的。逻辑回归模型表明，某些症状的存在，例如直肠出血和胃灼热，更有可能与晚期癌症而不是早期癌症有关。
Questionnaires were completed by a sample (n=53) of patients at two points in time, prior to surgery for colorectal cancer and three months thereafter. The questionnaires comprised the Nottingham Health Profile, as a general health status measure, and a specific checklist of 30 symptoms. Of the physical symptoms, loss of appetite, rectal bleeding and urgency of bowel movement appeared to decline after treatment, whilst other potential symptoms, such as vomiting, appeared to occur only rarely, both before and after surgery. Pre-treatment symptoms of psychological distress appeared to have dissipated by three months, suggesting that they were more likely to have resulted from the anticipation of treatment rather than from the disease itself. A logistic regression model suggests that the presence of certain symptoms, such as rectal bleeding and heartburn, is more likely to be associated with the presence of late- as opposed to early-stage cancer.