Long noncoding RNA amplified in lung cancer rewires cancer pathways.
Long noncoding RNA amplified in lung cancer rewires cancer pathways.
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肺癌中扩增的长非编码 RNA 重新连接了癌症通路。
DOI：
10.1083/jcb.202007098
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
Dimitrova,Nadya
中科院分区：
文献类型：
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作者：
Martínez-Terroba,Elena;Dimitrova,Nadya
Athie等人（2020. 201908078）鉴定ALAL-I，一种在肺癌中频繁扩增或过表达的lncRNA，作为致癌驱动因子，能够促进肺癌细胞的增殖并改变其免疫原性。
Athie et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.201908078) identify ALAL-1, a lncRNA frequently amplified or overexpressed in lung cancer, as an oncogenic driver, capable of promoting the proliferation and altering the immunogenicity of lung cancer cells.