Autobiographical memory specificity and the course of major depressive disorder
Autobiographical memory specificity and the course of major depressive disorder
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DOI：
10.1053/comp.2002.34635
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发表时间：
2002-09-01
影响因子：
7.3
通讯作者：
Boon-Vermeeren, M
中科院分区：
文献类型：
--
作者：
Peeters, F;Wessel, I;Boon-Vermeeren, M
这项研究检查了自传体记忆功能障碍的稳定性（即，提取特定记忆的困难），与早期不良经历的关系，以及对抑郁症病程的影响。使用自传体记忆测试（AMT），自传体记忆的特异性进行了评估，在25名受试者与目前的抑郁症在基线，并在3个月和7个月的后续行动。此外，还获得了有关自我报告的儿童期创伤以及人口统计学和临床变量的信息。自传体记忆表现相对稳定，随着时间的推移，尽管在样本的临床改善。它与基线时的抑郁严重程度无关，而较高水平的童年创伤与基线时对负面线索词的更具体的记忆表现相关，但在随访期间则无关。具体的自传体反应的负面线索词预测更好的预后，而具体的反应，积极的线索词与预后无关。抑郁症中的自传体记忆功能障碍似乎随时间推移而稳定，与抑郁症的短期预后有关，并可能作为影响抑郁症长期病程的脆弱性因素。版权所有2002，爱思唯尔科学（美国）。All rights reserved.
This study examined the stability of autobiographical memory dysfunction (i.e., difficulties in retrieving specific memories) during the course of major depressive disorder, its relation to early adverse experiences, and its influence on the course of depressive disorder. Using the Autobiographical Memory Test (AMT), specificity of autobiographical memory was assessed in 25 subjects with a current depressive disorder at baseline, and at 3 and 7 months follow-up. Also, information about self-reported childhood traumatization, and demographic and clinical variables was obtained. Autobiographical memory performance was relatively stable over time despite clinical improvement in the sample. It was not related to depression severity at baseline, while higher levels of childhood traumatization were correlated with more specific memory performance to negative cue words at baseline, but not during follow-up. Specific autobiographical responses to negative cue words predicted a better prognosis, whereas specific responses to positive cue words were not related to prognosis. Autobiographical memory dysfunction in depression appears to be stable over time, is related to short-term prognosis in depression, and may act as a vulnerability factor that influences the long-term course of depressive disorders. Copyright 2002, Elsevier Science (USA). All rights reserved.