Strengths and limitations of meta-analyses.

Strengths and limitations of meta-analyses.
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荟萃分析的优点和局限性。

DOI:
10.1093/eurheartj/ehab682
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发表时间:
2022
影响因子:
39.3
通讯作者:
Berry C
Berry C
中科院分区:
医学1区
文献类型:
--
作者:
Berry C

文献摘要

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荟萃分析的结果是多种因素的函数,尤其是任何时候的可用数据。在考虑荟萃分析的影响时,多元性也是相关的。不同的研究小组可能会就某一主题发表多项荟萃分析,其结果可能不一致。这些问题与个体患者数据汇总分析的相关性较低,我们同意这种方法的价值。对荟萃分析的证据进行批判性审查更为重要,因为它们优先考虑为临床实践指南提供信息。
The results of meta-analysis are a function of multiple factors, not least the available data at any moment in time. When considering the impact of a meta-analysis, plurality is also relevant. Multiple meta-analyses by different research groups may be published on a given topic, and their findings may not be coherent. These issues are less relevant to individual-patient data pooled analyses, and we agree on the value of this approach. A critical review of evidence from meta-analyses is all the more important given their prioritization to inform clinical practice guidelines.