Visualizing the structure and mechanism of a small nucleolytic ribozyme.
Visualizing the structure and mechanism of a small nucleolytic ribozyme.
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DOI：
10.1016/s1046-2023(02)00237-2
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发表时间：
2002-11
期刊：
影响因子：
4.8
通讯作者：
W. Scott
中科院分区：
文献类型：
--
作者：
W. Scott
Time-resolved crystallography has recently evolved into a powerful and invaluable technique for observing conformational and chemical intermediate states at or near atomic resolution in protein enzymes. The application of monochromatic time-resolved X-ray crystallographic freeze-trapping experiments to an RNA enzyme, the hammerhead ribozyme, is outlined here.
