Patient preferences for diabetes management among people with type 2 diabetes in Denmark - a discrete choice experiment
Patient preferences for diabetes management among people with type 2 diabetes in Denmark - a discrete choice experiment
复制标题
DOI：
10.1185/03007995.2011.625404
复制
发表时间：
2011-11-01
影响因子：
2.3
通讯作者：
Lammert, Morten
中科院分区：
文献类型：
--
作者：
Bogelund, Mette;Vilsboll, Tina;Lammert, Morten
Objectives：To study patient preferences for diabetes-treatment related attributes among people with type 2 diabetes.Research design and methods：参与者来自三个糖尿病门诊和两个全科医生手术。数据收集电子和结果进行了分析，使用一个标准的统计模型设计的选择集（条件logit），六个特点有关的治疗糖尿病进行了检查：糖化血红蛋白水平（HbA（1c）），体重（增益或损失），低血糖事件，需要注射，短暂的恶心和需要血糖testing.Results：二百七十名参与者与2型糖尿病（178名男性，92名女性）。患者最重视减肥，愿意为减掉6公斤体重付出最多。体重减轻3公斤是下一个高度重视的，其次是HbA（1c）水平下降一个百分点。避免恶心和减少低血糖事件从每月两个到没有也是高度重视。例如，如果患者同时减轻1.4公斤，他们愿意接受每天一次注射。这项研究的一个局限性是，调查是基于网络的，这样的调查的响应率可以是非常可变的。结论：2型糖尿病患者在丹麦愿意支付与改善糖尿病治疗相关的健康福利，其中最重要的是体重减轻或避免体重增加，降低糖化血红蛋白，和低血糖事件。
Objectives:To study patient preferences for diabetes-treatment related attributes among people with type 2 diabetes.Research design and methods:Participants were recruited from three diabetes out-patient clinics and two general practitioner surgeries. Data were collected electronically and results were analysed using a standard statistical model designed for choice sets (conditional logit), Six characteristics relating to treatment of diabetes were examined: glycated haemoglobin level (HbA(1c)), weight (gain or loss), hypoglycaemic events, need for injections, transient nausea and need for blood glucose testing.Results:Two hundred and seventy participants with type 2 diabetes (178 males, 92 females) were included. Patients placed the most value on losing weight and were willing to pay the most to lose 6 kg of weight. Loss of 3 kg of weight was the next highly valued, followed by dropping one percentage point in HbA(1c) level. Avoidance of nausea and a reduction in hypogaycaemic events from two per month to none was also highly valued. Patients were willing to accept one injection per day if they, for instance, simultaneously lost 1.4 kg. A limitation of the study is that the survey was web-based and response rates for such surveys can be extremely variable.Conclusion: Patients with type 2 diabetes in Denmark were willing to pay for the health benefits associated with improved diabetes treatment the most important of these being weight loss or avoidance of weight gain, and reduction of HbA1c, and of hypoglycaemic events.