Frequency of Panton-Valentine Leukocidin-Producing Methicillin-Sensitive Staphylococcus Strains in Patients with Complicated Skin and Soft Tissue Infection in Bronx, New York
Frequency of Panton-Valentine Leukocidin-Producing Methicillin-Sensitive Staphylococcus Strains in Patients with Complicated Skin and Soft Tissue Infection in Bronx, New York
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DOI：
10.1128/jcm.00704-11
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发表时间：
2011-08-01
影响因子：
9.4
通讯作者：
Fries, Bettina C.
中科院分区：
文献类型：
--
作者：
Kaltsas, Anna;Guh, Alice;Fries, Bettina C.
lukF-PV存在于36%的皮肤和软组织感染（SSTI）衍生的甲氧西林敏感金黄色葡萄球菌（MSSA）菌株中，并且包括6个不同的克隆，其含有比不含lukF-PV的菌株更少的肠毒素基因。lukF-PV（+）耐甲氧西林链球菌的临床表现和结局金黄色葡萄球菌（MRSA）和MSSA SSTI是相当的。在多变量分析中，lukF-PV的存在仍然是MSSA菌株中切口和引流的重要预测因素。
lukF-PV was present in 36% of skin and soft tissue infection (SSTI)-derived methicillin-susceptible Staphylococcus aureus (MSSA) strains and comprised six distinct clones, which contained fewer enterotoxin genes than strains without lukF-PV. Clinical presentations and outcomes of lukF-PV(+) methicillin-resistant S. aureus (MRSA) and MSSA SSTIs were comparable. In multivariable analysis, the presence of lukF-PV remained a significant predictor for incision and drainage among MSSA strains.