NECROTIZING ENTEROCOLITIS IN LOW-BIRTH-WEIGHT INFANTS FED AN ELEMENTAL FORMULA
NECROTIZING ENTEROCOLITIS IN LOW-BIRTH-WEIGHT INFANTS FED AN ELEMENTAL FORMULA
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DOI：
10.1016/s0022-3476(75)80835-3
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发表时间：
1975-01-01
影响因子：
5.1
通讯作者：
JUNG, AL
中科院分区：
文献类型：
--
作者：
BOOK, LS;HERBST, JJ;JUNG, AL
随着人们越来越重视极小婴儿的口服营养，新生儿坏死性小肠结肠炎的发病率有所增加。进行了一项前瞻性调查，以确定标准牛奶配方奶粉与元素配方奶粉相比的营养功效以及坏死性小肠结肠炎的发生率。 16 名体重低于 1,200 克的婴儿被随机分配并喂养两种配方奶粉中的一种。两组的临床状况相似。八分之七 (87.5%) 喂养元素配方奶粉的婴儿和八分之二 (25%) 喂养标准牛奶配方奶粉的婴儿出现了坏死性小肠结肠炎 (p<0.02)。元素饮食的高渗性可能导致喂养该配方奶粉的婴儿坏死性小肠结肠炎的发病率增加。
The incidence of necrotizing enterocolitis in the newborn infant has increased within the same time period that increasing emphasis has been placed on oral alimentation of very small infants. A prospective investigation was conducted to determine the nutritional efficacy as well as the incidence of necrotizing enterocolitis of a standard cow milk formula compared with an elemental formula. Sixteen infants who weighed less than 1,200 gm were randomized and fed one of the two formulas. The clinical status of the two groups was similar. Seven of eight (87.5%) infants fed the elemental formula and two of eight (25%) fed the standard cow milk formula developed necrotizing enterocolitis (p<0.02). The hypertonicity of the elemental diet may have contributed to the increased incidence of necrotizing enterocolitis in infants fed this formula.