Biology and toxicology of tellurium explored by speciation analysis.
Biology and toxicology of tellurium explored by speciation analysis.
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DOI：
10.1039/c7mt00022g
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发表时间：
2017-05
期刊：
影响因子：
--
通讯作者：
Y. Ogra
中科院分区：
文献类型：
--
作者：
Y. Ogra
碲(Te)具有独特的物理化学性质，在工业上得到了广泛的应用。虽然Te在动植物中是一种非必需元素，但在接触无机Te化合物的生物体中，Te有望被代谢成具有碳-Te键的有机金属化合物。因此，碲代谢物的形态和鉴定有望有助于描绘Te的代谢图。元素质谱仪的物种形成和分子质谱仪与分离技术相结合的鉴定极大地促进了动植物中硫代谢物的发现。这篇简短的综述旨在介绍碲的生物学和毒理学方面的最新进展，这些进展是通过分子质谱学的形态和鉴定揭示的。
Tellurium (Te) is widely used in industry because it has unique physicochemical properties. Although Te is a non-essential element in animals and plants, it is expected to be metabolized to organometallic compounds having a carbon-Te bond in living organisms exposed to inorganic Te compounds. Thus, the speciation and identification of tellurometabolites are expected to contribute to the depiction of the metabolic chart of Te. Speciation by elemental mass spectrometry and identification by molecular mass spectrometry coupled with separation techniques have significantly contributed to the discovery of tellurometabolites in animals and plants. The aim of this mini review is to present recent advances in the biology and toxicology of tellurium as revealed by speciation and identification by molecular mass spectrometry.