Assessing mental stress from the photoplethysmogram: a numerical study
Assessing mental stress from the photoplethysmogram: a numerical study
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DOI：
10.1088/1361-6579/aabe6a
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发表时间：
2018-05-01
影响因子：
3.2
通讯作者：
Alastruey, Jordi
中科院分区：
文献类型：
--
作者：
Charlton, Peter H.;Celka, Patrick;Alastruey, Jordi
目的：精神压力不利于心血管健康，是冠心病的危险因素和心脏事件的触发因素。然而，目前尚未对其进行常规评估。本研究的目的是确定光电体积描记图 (PPG) 脉搏波的特征，这些特征表明精神压力。方法：使用脉搏波传播的数值模型来模拟血压信号，并使用传递函数从中估计模拟的 PPG 脉搏波。根据与压力相关的血流动力学变化，通过同时和单独改变模型输入参数，在六个压力水平下模拟脉搏波。从三个测量部位的脉搏波中提取了 32 个特征测量值：肱动脉、桡动脉和颞动脉。使用曼-肯德尔单调趋势检验来识别随压力显着变化的特征。主要结果：17 个特征在至少一个站点的测量中表现出显着的压力趋势。三个特征在所有三个部位都显示出显着的趋势：从脉搏开始到峰值的时间、从重搏切迹到脉搏结束的时间以及脉搏率。与肱动脉 (8) 或颞动脉 (7) 相比，更多特征显示桡动脉 (15) 具有显着趋势。大多数特征都受到多个输入参数的影响。意义：本研究中确定的特征可用于监测医疗保健和消费设备中的压力。桡动脉的测量可以提供比肱动脉或颞动脉更好的性能。需要体内研究来证实这些观察结果。
Objective: Mental stress is detrimental to cardiovascular health, being a risk factor for coronary heart disease and a trigger for cardiac events. However, it is not currently routinely assessed. The aim of this study was to identify features of the photoplethysmogram (PPG) pulse wave which are indicative of mental stress. Approach: A numerical model of pulse wave propagation was used to simulate blood pressure signals, from which simulated PPG pulse waves were estimated using a transfer function. Pulse waves were simulated at six levels of stress by changing the model input parameters both simultaneously and individually, in accordance with haemodynamic changes associated with stress. Thirty-two feature measurements were extracted from pulse waves at three measurement sites: the brachial, radial and temporal arteries. Features which changed significantly with stress were identified using the Mann-Kendall monotonic trend test. Main results: Seventeen features exhibited significant trends with stress in measurements from at least one site. Three features showed significant trends at all three sites: the time from pulse onset to peak, the time from the dicrotic notch to pulse end, and the pulse rate. More features showed significant trends at the radial artery (15) than the brachial (8) or temporal (7) arteries. Most features were influenced by multiple input parameters. Significance: The features identified in this study could be used to monitor stress in healthcare and consumer devices. Measurements at the radial artery may provide superior performance than the brachial or temporal arteries. In vivo studies are required to confirm these observations.