Ulceroglandular tularemia in a toddler in Germany after a mosquito bite

Ulceroglandular tularemia in a toddler in Germany after a mosquito bite
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DOI:
10.1007/s00431-008-0862-3
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发表时间:
2009-08-01
影响因子:
3.6
通讯作者:
von Schnakenburg, Christian
von Schnakenburg, Christian
中科院分区:
医学3区
文献类型:
--
作者:
Hanke, Christof A.;Otten, Joerg-Elard;von Schnakenburg, Christian

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虽然土拉菌病是一种众所周知的疾病,但在过去的几十年里,它在中欧的重要性已经减弱。然而,在过去的几年里,有新的证据表明兔热病在德国重新出现。2007年,报告的人间病例数量达到近50年来的最高水平。除了典型的病媒之外,新的传播方式似乎也越来越重要。到目前为止,蚊子叮咬传播的兔热病只在斯堪的纳维亚半岛发现,而在中欧还没有发现。病例报告我们报告的第一例1岁的幼儿从西南部德国与蚊子叮咬相关的溃疡腺土拉菌病。该病例的新的和有趣的特点是患者的年轻和不寻常的传播途径。现有的数据表明,在德国的土拉菌病的流行病学变化进行审查。这是一个有趣的婴儿土拉菌病病例,具有非常不寻常的传播途径,突出了德国土拉菌病流行病学的持续变化。
Introduction Although tularemia is a long-known disease, its significance had diminished over the last decades in Middle Europe. However, over the past years, there is new evidence suggesting that tularemia has re-emerged in Germany. In 2007, the highest number of human cases for almost 50 years has been notified. Beside typical vectors, new ways of transmission seem to gain significance. So far, mosquito bite-transmitted tularemia has only been known from Scandinavia but not from Middle Europe. Case report We report the first case of a 1-year-old toddler from Southwestern Germany with mosquito bite-associated ulceroglandular tularaemia. The new and interesting features of this case are the young age of the patient and the unusual transmission route. The available data suggesting changes in the epidemiology for tularemia in Germany are reviewed. This is an interesting case of infantile tularemia with a very unusual transmission route, highlighting ongoing changes in the epidemiology of tularemia in Germany.