Task dependency of the long-latency facilitatory effect on the soleus H-reflex by cerebellar transcranial magnetic stimulation
Task dependency of the long-latency facilitatory effect on the soleus H-reflex by cerebellar transcranial magnetic stimulation
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DOI：
10.1097/wnr.0000000000000275
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发表时间：
2014-12-03
期刊：
影响因子：
1.7
通讯作者：
Nagano, Kiyoshi
中科院分区：
文献类型：
--
作者：
Matsugi, Akiyoshi;Mori, Nobuhiko;Nagano, Kiyoshi
我们研究了小脑经颅磁刺激（C-TMS）是否促进了休息时同侧比目鱼运动神经元池的兴奋性，以及这种促进是否受到促进小脑活动的任务的调节。在C-TMS之前或之后，在俯卧的个体中进行一项激发右比目鱼肌h反射的胫骨神经刺激试验。条件反射在110、120和130 ms间刺激时，h反射的振幅显著增加。此外，我们发现当个体轻敲右手食指时，这种促进作用被抑制。这些发现表明，C-TMS促进了脊髓运动神经元的兴奋性，其潜伏期与静息时的100ms相似，并且这种小脑脊髓促进性是由可能增加小脑活动的任务调节的。因此，小脑脊髓易化可用于评估小脑的兴奋性，或小脑对脊髓运动神经元的输出。(C) 2014年Wolters Kluwer Health垂直条Lippincott Williams & Wilkins。
We investigated whether cerebellar transcranial magnetic stimulation (C-TMS) facilitates the excitability of the ipsilateral soleus motoneuron pool in resting humans, and whether the facilitation is modulated by a task that promotes cerebellar activity. A test tibial nerve stimulus evoking the H-reflex from the right soleus muscle was delivered before or after conditioning C-TMS in prone individuals. The amplitude of the H-reflex was significantly increased at conditioning-test interstimulus intervals of 110, 120, and 130 ms. Furthermore, we revealed that this facilitation effect was inhibited while the individuals tapped their right index finger. These findings indicate that C-TMS facilitates spinal motoneuronal excitability with an similar to 100ms latency in resting humans, and that this cerebellar spinal facilitation is modulated by a task that might increase cerebellar activity. Cerebellar spinal facilitation could thus be useful for assessing the excitability of the cerebellum, or the cerebellar output to spinal motoneurons. (C) 2014 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.