Proton MR spectroscopy and imaging of the brain in AIDS: evidence of neuronal loss in regions that appear normal with imaging.
Proton MR spectroscopy and imaging of the brain in AIDS: evidence of neuronal loss in regions that appear normal with imaging.
复制标题
艾滋病大脑的质子磁共振波谱和成像：成像正常区域神经元损失的证据。
DOI：
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发表时间：
1990
影响因子：
1.3
通讯作者：
C. Hoyle
中科院分区：
文献类型：
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作者：
D. Menon;C. Baudouin;D. Tomlinson;C. Hoyle
中枢神经系统受累越来越被认为是获得性免疫缺陷综合征（AIDS）的一种常见表现，或者是人类免疫缺陷病毒的直接影响，或者是继发感染或恶性肿瘤的结果。一部分有临床或心理学证据表明中枢神经系统受累的患者在影像学上表现正常。本报告描述了质子磁共振波谱（1H MRS）在两名艾滋病患者，并讨论了1H MRS的作用，在提供一个标记的神经元损失的患者与正常或边界成像。
Central nervous system involvement is increasingly being recognised as a common manifestation of the acquired immunodeficiency syndrome (AIDS), either as a direct effect of the human immunodeficiency virus, or as a result of secondary infection or malignancy. A subset of patients with clinical or psychometric evidence of CNS involvement have normal appearances on imaging. This report describes proton magnetic resonance spectroscopy (1H MRS) in two patients with AIDS and discusses the role of 1H MRS in providing a marker of neuronal loss in patients with normal or borderline imaging.