Association of depressive symptoms and metabolic syndrome in men
Association of depressive symptoms and metabolic syndrome in men
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DOI：
10.1111/j.1600-0447.2008.01333.x
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发表时间：
2009-07-01
影响因子：
6.7
通讯作者：
Hintikka, J.
中科院分区：
文献类型：
--
作者：
Viinamaki, H.;Heiskanen, T.;Hintikka, J.
目的：探讨抑郁症多项指标与代谢综合征（MetS）的关系。方法：以人群为基础的高（HMS组）或低（LMS组）精神症状（包括抑郁症）水平的样本，参加了2005年的临床检查（n = 223）。根据NCEP标准确定MetS。结果：met的患病率男性为49%，女性为21%。患有met的男性患重度抑郁症的比例高于其他男性。他们也表现出更高的汉密尔顿抑郁量表（HDRS）得分和更多的自杀迹象。在logistic回归分析中，较高的HDRS评分（OR 1.31, 95% CI 1.04-1.64）和属于HMS组（OR 10.1, 95% CI 1.98-51.3）是MetS的独立关联，但仅适用于男性。结论：结果强调长期抑郁症状与MetS的出现之间存在关联，特别是在男性中。
Objective: To explore the relationship between several indicators of depression and metabolic syndrome (MetS).Method: A population-based sample with high (HMS group) or low (LMS group) levels of mental symptoms, including those of depression, in three follow-ups participated in a clinical examination in 2005 (n = 223). MetS was determined according to the NCEP criteria.Results: The prevalence of MetS was 49% in men and 21% in women. Men with MetS had higher rates of major depressive disorder than other men. They also displayed higher Hamilton Rating Scale for Depression (HDRS) scores and more often signs of suicidality. In logistic regression analyses, higher HDRS scores (OR 1.31, 95% CI 1.04-1.64) and belonging to the HMS group (OR 10.1, 95% CI 1.98-51.3) were independent associates for MetS but only in men.Conclusion: The results highlight that there is an association between long-term depressive symptoms and the emergence of MetS, especially in men.