Editorial comment--the MOST score: modifying the open-artery "good"-closed-artery "bad" approach to thrombolysis prognosis.

Editorial comment--the MOST score: modifying the open-artery "good"-closed-artery "bad" approach to thrombolysis prognosis.
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编辑评论——MOST评分:修改开放动脉“好”-封闭动脉“坏”的溶栓预后方法。

DOI:
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发表时间:
2003
期刊:
影响因子:
8.3
通讯作者:
R. Felberg
R. Felberg
中科院分区:
医学1区
文献类型:
--
作者:
R. Felberg

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再通的速度和程度已被证明可以预测急性缺血性卒中溶栓治疗的良好结局。1,2然而,尽管完全再通,许多患者仍然表现不佳。有些患者的功能从未恢复,而另一些患者则在改善3或症状性脑出血后出现恶化。相反,许多患者经历完全恢复,尽管持续的血管阻塞。几个临床因素已被证明可预测不良结局,包括持续动脉闭塞、缓慢再通、高血糖、收缩期高血压和基线CT扫描的早期缺血性变化。4,5 在本报告中,Molina等人前瞻性收集了经颅多普勒(TCD)证实大脑中动脉闭塞的急性卒中综合征患者,并使用标准静脉注射组织纤溶酶原激活剂(tPA)方案进行治疗。6检查了血流动力学、放射学、实验室和临床数据,...
The rapidity and degree of recanalization has been shown to predict good outcome in thrombolysis of acute ischemic stroke.1,2 However, despite complete recanalization, many patients continue to do poorly. Some never recover function, while others experience deterioration after improvement3 or symptomatic intracerebral hemorrhage. Conversely, many patients experience complete recovery despite continued vessel obstruction. Several clinical factors have been shown to predict poor outcome including continued arterial occlusion, slow recanalization, hyperglycemia, systolic hypertension, and early ischemic changes on the baseline CT scan.4,5 In this report, Molina et al prospectively collected patients who presented with acute stroke syndromes with transcranial Doppler (TCD)-demonstrated middle cerebral artery occlusions and were treated using standard intravenous tissue plasminogen activator (tPA) protocols.6 Hemodynamic, radiologic, laboratory, and clinical data were examined, …
DOI: 10.1161/01.str.31.4.915
发表时间: 2000-04-01
期刊: STROKE
影响因子: 8.3
作者:
Alexandrov, AV;Felberg, RA;Grotta, JC
通讯作者: Grotta, JC
DOI: 10.1161/01.str.31.8.1812
发表时间: 2000-08-01
期刊: STROKE
影响因子: 8.3
作者:
Christou, I;Alexandrov, AV;Grotta, JC
通讯作者: Grotta, JC