Intraventricular hemorrhage from ruptured aneurysm: clinical characteristics, complications, and outcomes in a large, prospective, multicenter study population
Intraventricular hemorrhage from ruptured aneurysm: clinical characteristics, complications, and outcomes in a large, prospective, multicenter study population
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DOI：
10.3171/jns-07/08/0261
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发表时间：
2007-08-01
影响因子：
4.1
通讯作者：
Rosengart, Axel J.
中科院分区：
文献类型：
--
作者：
Rosen, David S.;Macdonald, R. Loch;Rosengart, Axel J.
物体。在这项研究中，作者分析了大量脑室出血(IVH)与院内并发症和临床结局的关系。对3539例动脉瘤性蛛网膜下腔出血患者的数据进行了评估，这些数据来自1991至1997年间进行的四项替拉扎德前瞻性、随机、双盲、安慰剂对照试验。分析SAH后3个月的临床特征、住院并发症和预后(格拉斯哥预后评分)是否存在IVH。SAH和IVH患者在人口学和入院特征上与SAH但无IVH的患者不同，SAH后3个月更容易发生住院并发症，预后更差。在SAH患者中出现IVH在这些方面具有重要的预测价值。
Object. In this study the authors analyzed the relationship of intraventricular hemorrhage (IVH) to in-hospital complications and clinical outcome in a large population of patients with aneurysmal subarachnoid hemorrhage (SAH).Methods. Data from 3539 patients with aneurysmal SAH were evaluated, and these data were obtained from four prospective, randomized, double-blind, placebo-controlled trials of tirilazad that had been conducted between 1991 and 1997. Clinical characteristics, in-hospital complications, and outcome at 3 months post-SAH (Glasgow Outcome Scale score) were analyzed with regard to the presence or absence of IVH.Results. Patients with SAH and IVH differ in demographic and admission characteristics from those with SAH but without IVH and are more likely to suffer in-hospital complications and a worse outcome at 3 months post-SAH.Conclusions. The presence of IVH in patients with SAH has an important predictive value with regard to these aspects.