Perceptual Structure of Adductor Spasmodic Dysphonia and Its Acoustic Correlates

Perceptual Structure of Adductor Spasmodic Dysphonia and Its Acoustic Correlates
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DOI:
10.1016/j.jvoice.2012.05.005
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发表时间:
2012-11-01
期刊:
影响因子:
2.2
通讯作者:
Woodson, Gayle E.
Woodson, Gayle E.
中科院分区:
医学3区
文献类型:
--
作者:
Cannito, Michael P.;Doiuchi, Maki;Woodson, Gayle E.

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目标.研究内收肌痉挛性发声障碍(ADSD)患者肉毒毒素治疗前后嗓音属性的感知结构,并确定潜在感知因素的声学相关性。感性判断的可靠性被认为是详细。研究设计。治疗前和治疗后的试验与健康对照组相比,使用单盲随机听者判断声音质量,以及与声学测量的回顾性比较。口头阅读记录从42 ADSD扬声器治疗前后,以及从他们的年龄和性别匹配的控制。经验丰富的法官听取了语音样本和评级的整体语音质量,呼吸,粗糙度和破碎的属性,使用计算机实现的视觉模拟缩放。对数据进行调整,以回归到平均值,并提交主成分因子分析。从阅读样本中提取的声波波形进行了分析,并将测量结果与感知因子评分进行了相关性分析。ADSD语音的四个可靠的感知变量被有效地减少到两个基本因素,对应于内收过度,最强烈的粗糙度,和内收不足,最强烈的呼吸。治疗后,高内收因子改善,而低内收因子恶化。感知粗糙度与四种声学指标之间存在统计学显著相关性(P < 0.01),而呼吸与非周期性和倒谱峰突出度(CPPs)相关。本研究支持ADSD的双因素模型,提示治疗前后内收过度和内收不足的知觉表征。这些因素对治疗的反应与以前的研究一致。感知和声学变量之间的相关性表明,多个声学特征有助于粗糙度的整体印象。虽然CPP似乎是一个部分相关的感知呼吸,这种感知的物理基础仍然不太清楚。
Objectives. To examine the perceptual structure of voice attributes in adductor spasmodic dysphonia (ADSD) before and after botulinum toxin treatment and identify acoustic correlates of underlying perceptual factors. Reliability of perceptual judgments is considered in detail.Study Design. Pre- and posttreatment trial with comparison to healthy controls, using single-blind randomized listener judgments of voice qualities, as well as retrospective comparison with acoustic measurements.Methods. Oral readings were recorded from 42 ADSD speakers before and after treatment as well as from their age- and sex-matched controls. Experienced judges listened to speech samples and rated attributes of overall voice quality, breathiness, roughness, and brokenness, using computer-implemented visual analog scaling. Data were adjusted for regression to the mean and submitted to principal components factor analysis. Acoustic waveforms, extracted from the reading samples, were analyzed and measurements correlated with perceptual factor scores.Results. Four reliable perceptual variables of ADSD voice were effectively reduced to two underlying factors that corresponded to hyperadduction, most strongly associated with roughness, and hypoadduction, most strongly associated with breathiness. After treatment, the hyperadduction factor improved, whereas the hypoadduction factor worsened. Statistically significant (P < 0.01) correlations were observed between perceived roughness and four acoustic measures, whereas breathiness correlated with aperiodicity and cepstral peak prominence (CPPs).Conclusions. This study supported a two-factor model of ADSD, suggesting perceptual characterization by both hyperadduction and hypoadduction before and after treatment. Responses of the factors to treatment were consistent with previous research. Correlations among perceptual and acoustic variables suggested that multiple acoustic features contributed to the overall impression of roughness. Although CPPs appears to be a partial correlate of perceived breathiness, a physical basis of this percept remained less clear.