Multiplex particle focusing via hydrodynamic force in viscoelastic fluids.
Multiplex particle focusing via hydrodynamic force in viscoelastic fluids.
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DOI：
10.1038/srep03258
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发表时间：
2013-11-19
影响因子：
4.6
通讯作者：
Song YS
中科院分区：
文献类型：
--
作者：
Lee DJ;Brenner H;Youn JR;Song YS
我们介绍了微流体装置中粘弹性力和迪安曳力之间的流体动力相互作用产生的多重粒子聚焦现象。在有限的微通道中，粘弹性流体的第一法向应力差导致悬浮颗粒的横向迁移。利用这种粘弹性力将不同尺寸的颗粒集中在微通道的中间，并且还考虑了螺旋通道的几何形状，以便利用反作用力，即诱导颗粒向外方向迁移的迪恩拖曳力。为了理论理解，我们对螺旋微流体通道中的粘弹性流体进行了数值分析。根据这些结果，提出了“迪安耦合弹惯性聚焦带（DEF）”的概念。这项研究提供了对粒子多重聚焦的深入物理见解，可以为微尺度混凝土高通量平台的微流体粒子动力学开辟新的场所。
We introduce a multiplex particle focusing phenomenon that arises from the hydrodynamic interaction between the viscoelastic force and the Dean drag force in a microfluidic device. In a confined microchannel, the first normal stress difference of viscoelastic fluids results in a lateral migration of suspended particles. Such a viscoelastic force was harnessed to focus different sized particles in the middle of a microchannel, and spiral channel geometry was also considered in order to take advantage of the counteracting force, Dean drag force that induces particle migration in the outward direction. For theoretical understanding, we performed a numerical analysis of viscoelastic fluids in the spiral microfluidic channel. From these results, a concept of the ‘Dean-coupled Elasto-inertial Focusing band (DEF)' was proposed. This study provides in-depth physical insight into the multiplex focusing of particles that can open a new venue for microfluidic particle dynamics for a concrete high throughput platform at microscale.