PsyGeNET: a knowledge platform on psychiatric disorders and their genes.
PsyGeNET: a knowledge platform on psychiatric disorders and their genes.
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DOI：
10.1093/bioinformatics/btv301
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发表时间：
2015-09-15
期刊：
影响因子：
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通讯作者：
Furlong LI
中科院分区：
文献类型：
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作者：
Gutiérrez-Sacristán A;Grosdidier S;Valverde O;Torrens M;Bravo À;Piñero J;Sanz F;Furlong LI
摘要：Psygenet（精神疾病和基因协会网络）是一个知识平台，用于对精神病及其相关基因进行探索性分析。 Psygenet由数据库和一个支持数据搜索，可视化，过滤和共享的Web接口组成。 Psygenet整合了Disgenet的信息，并通过文本挖掘从文献中提取的数据集成了该信息，该信息已由域专家策划。它目前包含1271个基因和37个精神病概念之间的2642个关联。 Psygenet在第一个版本中专注于三种精神疾病：严重的抑郁症，酒精和可卡因使用障碍。 Psygenet代表了一种全面的开放访问资源，用于分析基于精神疾病的分子机制及其合并症。
可用性和实现：Pysgenet平台可在http://www.psygenet.org/上自由获得。 PSYGENET数据库可在Open数据库许可证（http://opendatacommons.org/licenses/odbl/1.0/）下提供。
联系人：lfurlong@imim.es
补充信息：可以在线生物信息学上获得补充数据。
Summary: PsyGeNET (Psychiatric disorders and Genes association NETwork) is a knowledge platform for the exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of a database and a web interface supporting data search, visualization, filtering and sharing. PsyGeNET integrates information from DisGeNET and data extracted from the literature by text mining, which has been curated by domain experts. It currently contains 2642 associations between 1271 genes and 37 psychiatric disease concepts. In its first release, PsyGeNET is focused on three psychiatric disorders: major depression, alcohol and cocaine use disorders. PsyGeNET represents a comprehensive, open access resource for the analysis of the molecular mechanisms underpinning psychiatric disorders and their comorbidities. Availability and implementation: The PysGeNET platform is freely available at http://www.psygenet.org/. The PsyGeNET database is made available under the Open Database License (http://opendatacommons.org/licenses/odbl/1.0/). Contact: lfurlong@imim.es Supplementary information: Supplementary data are available at Bioinformatics online.