Prevalence and characteristics of dysarthria in a multiple-sclerosis incidence cohort: Relation to neurological data
Prevalence and characteristics of dysarthria in a multiple-sclerosis incidence cohort: Relation to neurological data
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DOI：
10.1159/000021531
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发表时间：
2000-07-01
影响因子：
1
通讯作者：
Andersen, O
中科院分区：
文献类型：
--
作者：
Hartelius, L;Runmarker, B;Andersen, O
很少有人尝试利用多发性硬化症 (MS) 构音障碍的程度和类型进行神经学评估。在本研究中，语言病理学家和神经学家对来自多发性硬化症人群的 77 名个体进行了检查，随后将来自三个信息源的数据结合起来：（1）临床构音障碍测试程序，（2）连续言语中言语特征的感知分析，以及（3）神经缺陷评分。还对 15 名年龄和性别匹配的健康对照受试者的言语进行了调查。结论是：（I）该队列中轻度至重度构音障碍的患病率为 51%，发生在言语产生的所有组成部分：呼吸、发声、韵律、发音和鼻音。 (2)临床构音障碍测试对于检测亚临床言语体征敏感。根据测试发现，病理性语言体征的患病率为 62%。仅根据神经学评估，构音障碍的患病率为 20%。 (3) MS 的构音障碍主要是混合性构音障碍，在特定个体的言语中经常出现共济失调和痉挛性言语体征。 (4)此外，当存在主要类型的构音障碍时，它通常与神经功能缺陷的特征性特征无关。相反，言语偏差的严重程度与神经系统受累的总体严重程度、病程类型和进展年数呈正相关。版权所有 (C) 2000 S. Karger AG。巴塞尔。
Few attempts have been made to use degree and type of multiple sclerosis (MS) dysarthria in neurological evaluation. In the present study, 77 individuals drawn from an MS population were examined both by a speech pathologist and a neurologist, and data from three sources of information were subsequently combined: (1) a clinical dysarthria test procedure, (2) a perceptual analysis of speech characteristics in continuous speech, and (3) neurological deficit scoring, The speech of 15 age- and gender-matched healthy control subjects was also investigated. It was concluded that: (I)the prevalence of mild to severe dysarthria in this cohort was 51% and occurred in all components of speech production: respiration, phonation, prosody, articulation and nasality. (2) The clinical dysarthria test was sensitive in detecting subclinical speech signs. The prevalence of pathologic speech signs found on the basis of the test was found to be 62%. The prevalence of dysarthria based on the neurological evaluation alone was 20%. (3) The dysarthria of MS was a predominantly mixed dysarthria, with both ataxic and spastic speech signs frequently present in the speech of a given individual. (4) Furthermore, when a predominant type of dysarthria existed, it was not generally associated with a characteristic profile of neurological deficits. Rather, severity of speech deviation was positively correlated to overall severity of neurological involvement, type of disease course, and number of years in progression. Copyright (C) 2000 S. Karger AG. Basel.