Singapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes
Singapore Indian Eye Study-2: methodology and impact of migration on systemic and eye outcomes
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DOI：
10.1111/ceo.12974
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发表时间：
2017-11-01
影响因子：
4
通讯作者：
Wong, Tien Yin
中科院分区：
文献类型：
--
作者：
Sabanayagam, Charumathi;Yip, Wanfen;Wong, Tien Yin
亚裔印度人是世界上增长最快的移民群体。我们描述了新加坡印第安人眼科研究-2(SINDI-2)的方法，该研究旨在评估移民状况对生活在城市环境中的亚洲印度人中糖尿病视网膜病变和其他主要年龄相关眼病的影响。设计基于人口的队列研究。参与者共有2200名成年人参加了基线SINDI(2007-2009，平均年龄[范围]=57.8[42.7-84.1]岁)和SINDI-2(2013-2015，如果他们是在新加坡以外出生的印度居民，则被归类为第一代，如果他们出生在新加坡，则被归类为第二代移民(Sindi-2组为63.6%，Sindi-2组为59.7%)。主要结果指标根据移民状况对应答率、参与者特征和系统性疾病的患病率进行分层。在Sindi和Sindi-2，与第一代移民相比，第二代移民更年轻，更不可能有收入
ImportanceAsian Indians are the fastest growing migration groups in the world. Studies evaluating the impact of migration on disease outcomes in this population are rare.BackgroundWe describe the methodology of the Singapore Indian Eye Study-2 (SINDI-2) aimed to evaluate the impact of migration status on diabetic retinopathy and other major age-related eye diseases in Asian Indians living in an urban environment.DesignPopulation-based cohort study.ParticipantsA total of 2200 adults had participated in baseline SINDI (2007-2009, mean age [range]=57.8 [42.7-84.1]years) and SINDI-2 (2013-2015, 56.5 [48.4-90.2]years).MethodsParticipants were classified as first generation' if they were Indian residents born outside of Singapore and as second-generation' immigrants (59.7% in SINDI vs. 63.6% in SINDI-2) if they were born in Singapore.Main Outcome MeasuresResponse rate, participant characteristics and prevalence of systemic diseases were stratified by migration status.ResultsOf the 2914 eligible SINDI participants invited to participate, 2200 participated in SINDI-2 (response rate of 75.2%). In both SINDI and SINDI-2, compared with first-generation immigrants, second-generation immigrants were younger, less likely to have income