Sensitivity analysis for trend tests: application to the risk of radiation exposure
Sensitivity analysis for trend tests: application to the risk of radiation exposure
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DOI：
10.1093/biostatistics/kxi003
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发表时间：
2005-04-01
期刊：
影响因子：
2.1
通讯作者：
Gastwirth, JL
中科院分区：
文献类型：
--
作者：
Yu, BB;Gastwirth, JL
趋势检验用于评估多水平治疗 X 和二元反应 R 之间的关系。然而，在观察性研究中，可能存在与治疗 X 相关且与反应 R 因果相关的混杂因素 U。当未观察到混杂因素 U 的数据时，提供了一种评估测试结果对 U 的敏感性的方法。通过检查切尔诺贝利事故后突变率研究的数据来说明其用途。
Trend tests are used to assess the relationship between multiple level treatment X and binary response R. In observational studies, however, there may be a confounder U that is associated with treatment X and causally related to response R. When the data for the confounder U are not observed, an approach for assessing the sensitivity of test results to U is provided. Its use is illustrated by examining data from a study of mutation rate after the Chernobyl accident.