PHASE DIFFERENCE BETWEEN LOW-FREQUENCY OSCILLATIONS OF CEREBRAL DEOXY- AND OXY-HEMOGLOBIN CONCENTRATIONS DURING A MENTAL TASK.
PHASE DIFFERENCE BETWEEN LOW-FREQUENCY OSCILLATIONS OF CEREBRAL DEOXY- AND OXY-HEMOGLOBIN CONCENTRATIONS DURING A MENTAL TASK.
复制标题
脑力任务期间大脑脱氧血红蛋白和氧合血红蛋白浓度低频振荡之间的相位差。
DOI：
10.1142/s1793545811001332
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发表时间：
2011
影响因子：
2.5
通讯作者：
Fantini,Sergio
中科院分区：
文献类型：
--
作者：
Sassaroli,Angelo;Zheng,Feng;Pierro,Michele;Bergethon,PeterR;Fantini,Sergio
近红外光谱技术在脑中检测到的血流动力学低频（~0.1 Hz）自发振荡在脑激活、脑自动调节和功能连接的研究中具有潜在的应用。在这项工作中，我们已经调查了大脑脱氧和氧合血红蛋白浓度在0.05-0.10 Hz的频率范围内的振荡之间的相位滞后在人类受试者在精神负荷任务。我们用两种不同的方法得到了这种相位滞后的度量：（1）混沌振子理论中的相位同步分析和（2）一种新的互相关相量方法。这两种方法产生了一个较大的相位滞后之间的低频振荡的脱氧和氧合血红蛋白浓度在心理工作负荷的控制，休息条件的初步结果。
Hemodynamic low-frequency (~0.1 Hz) spontaneous oscillations as detected in the brain by near-infrared spectroscopy have potential applications in the study of brain activation, cerebral autoregulation, and functional connectivity. In this work, we have investigated the phase lag between oscillations of cerebral deoxy- and oxy-hemoglobin concentrations in the frequency range 0.05–0.10 Hz in a human subject during a mental workload task. We have obtained a measure of such phase lag using two different methods: (1) phase synchronization analysis as used in the theory of chaotic oscillators and (2) a novel cross-correlation phasor approach. The two methods yielded comparable initial results of a larger phase lag between low-frequency oscillations of deoxy- and oxy-hemoglobin concentrations during mental workload with respect to a control, rest condition.