Fluorescein and indocyanine green angiography findings in a case of poststreptococcal syndrome with erythema nodosum and posterior uveitis
Fluorescein and indocyanine green angiography findings in a case of poststreptococcal syndrome with erythema nodosum and posterior uveitis
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DOI：
10.1097/00006982-200112000-00020
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发表时间：
2001-01-01
影响因子：
3.3
通讯作者：
Mignemi, L
中科院分区：
文献类型：
--
作者：
Caccavale, A;Mignemi, L
链球菌感染后综合征（PSS）是一种累及多个器官的全身性自身免疫反应。风湿热、肾小球肾炎和结节性红斑是PSS最常见的临床表现。前葡萄膜炎和较不常见的后葡萄膜炎以前被报道为PSS的眼部表现。结节性红斑是多种感染性和自身免疫性疾病的皮肤征象。EN更常见的原因是上呼吸道链球菌感染后。结节性红斑的组织病理学特征是对皮下组织中小血管的嗜酸性反应所特有的，伴有炎性浸润和血管内纤维蛋白沉积伴血管闭塞。我们描述了一例链球菌感染后EN和双侧脉络膜炎，其特征是急性后部多灶性片状色素上皮病。根据吲哚菁绿色（ICG）和荧光素血管造影（FA）图像，讨论了脉络膜炎的发病机制。
Poststreptococcal syndrome (PSS) is a systemic autoimmune reaction that involves various organs. Rheumatic fever, glomerulonephritis, and erythema nodosum (EN) are the most common clinical manifestations of PSS. Anterior uveitis and, less frequently, posterior uveitis were previously reported as ocular manifestations of PSS. 1, 2 Erythema nodosum is a cutaneous sign of several kinds of infectious and autoimmune diseases. The more common cause of EN is after an upper airway streptococcal infection. Erythema nodosum’s histopathologic features are peculiar to a neutrophilic reaction against the small vessels in the subcutaneous tissue with an inflammatory infiltrate and intravascular fibrin deposition with vascular occlusion. We describe a case of poststreptococcal EN and bilateral choroiditis with the features of acute posterior multifocal placoid pigment epitheliopathy. The pathogenesis of the choroiditis is discussed on the grounds of the indocyanine green (ICG) and fluorescein angiography (FA) images.