STRUCTURE ELUCIDATION OF THE FUMONISINS, MYCOTOXINS FROM FUSARIUM-MONILIFORME
STRUCTURE ELUCIDATION OF THE FUMONISINS, MYCOTOXINS FROM FUSARIUM-MONILIFORME
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DOI：
10.1039/c39880000743
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发表时间：
1988-06-01
影响因子：
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通讯作者：
VLEGGAAR, R
中科院分区：
文献类型：
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作者：
BEZUIDENHOUT, SC;GELDERBLOM, WCA;VLEGGAAR, R
伏马菌素是从串珠镰刀菌培养物中分离出来的一类结构相关的霉菌毒素，通过质谱和 1H 和 13C nmr 阐明了其结构。光谱学为丙烷-1,2,3-三甲酸与2-乙酰氨基-或2-氨基-12,16-二甲基-3,5,10,14,15-五羟基二十烷以及每种情况下的C-10脱氧类似物的二酯；在所有情况下，C-14和C-15羟基都参与与丙烷-1,2,3-三羧酸的末端羧基形成酯。
The structures of the fumonisins, a family of structurally related mycotoxins isolated from cultures of Fusarium moniliforme, were elucidated by mass spectrometry and 1H and 13C n.m.r. spectroscopy as the diester of propane-1,2,3-tricarboxylic acid and either 2-acetylamino- or 2-amino-12,16-dimethyl-3,5,10,14,15-pentahydroxyicosane as well as in each case the C-10 deoxy analogue; in all cases both the C-14 and C-15 hydroxy groups are involved in ester formation with the terminal carboxy group of propane-1,2,3-tricarboxylic acid.