Enantioselective synthesis of epigallocatechin-3-gallate (EGCG), the active polyphenol component from green tea
Enantioselective synthesis of epigallocatechin-3-gallate (EGCG), the active polyphenol component from green tea
复制标题
DOI：
10.1021/ol000394z
复制
发表时间：
2001-03-08
期刊：
影响因子：
5.2
通讯作者：
Chan, TH
中科院分区：
文献类型：
--
作者：
Li, LH;Chan, TH
[图谱]采用Sharpless不对称二羟基化产物7 c的立体选择性环化反应作为关键步骤，实现了绿色茶中活性多酚成分表没食子儿茶素-3-没食子酸酯（EGCG，3b）的对映选择性合成。
[GRAPHICS]Enantioselective synthesis of epigallocatechin-3-gallate (EGCG, 3b), the active polyphenol component from green tea, has been achieved by using a stereospecific cyclization of the Sharpless asymmetric dihydroxylation product 7c as the key step.