Triggering up states in all-to-all coupled neurons
Triggering up states in all-to-all coupled neurons
复制标题
触发所有耦合神经元的状态
DOI：
10.1209/0295-5075/89/68002
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
H. Schuster
中科院分区：
文献类型：
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作者：
H. Ngo;Jan Kohler;J. Mayer;J. Claussen;H. Schuster
哺乳动物慢波睡眠的特点是大规模皮质活动的变化，目前被解释为皮质上/下状态。最近的一项实验证明了雪貂切片的双稳态集体行为，其显着特性是可以通过相同极性的脉冲或激励来打开和关闭向上状态；由此，第二个脉冲的效果很大程度上取决于脉冲之间的时间间隔。在这里，我们提出了一个简单的神经网络时间离散模型，它表现出这种类型的行为，并定量地再现了实验中发现的时间依赖性。
Slow-wave sleep in mammalians is characterized by a change of large-scale cortical activity currently paraphrased as cortical Up/Down states. A recent experiment demonstrated a bistable collective behaviour in ferret slices, with the remarkable property that the Up states can be switched on and off with pulses, or excitations, of same polarity; whereby the effect of the second pulse significantly depends on the time interval between the pulses. Here we present a simple time-discrete model of a neural network that exhibits this type of behaviour, as well as quantitatively reproduces the time dependence found in the experiments.