Eating Disorders in Girls and Women With Type 1 Diabetes: A Longitudinal Study of Prevalence, Onset, Remission, and Recurrence
Eating Disorders in Girls and Women With Type 1 Diabetes: A Longitudinal Study of Prevalence, Onset, Remission, and Recurrence
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DOI：
10.2337/dc14-2646
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发表时间：
2015-07-01
期刊：
影响因子：
16.2
通讯作者：
Rodin, Gary M.
中科院分区：
文献类型：
--
作者：
Colton, Patricia A.;Olmsted, Marion P.;Rodin, Gary M.
1型糖尿病的女性和女孩患饮食失调症（ED）的风险增加，这些疾病与严重的糖尿病相关的医疗并发症有关。本研究描述了纵向过程中的饮食行为（DEB）和ED在队列与1型diabetes.Research设计和METHODSA共126名女孩与1型糖尿病接受糖尿病护理在医院为患病儿童在多伦多参加了一系列的7个访谈为基础的评估艾德的行为和精神病理学超过14年的时间，开始在童年后期。使用生存分析。平均年龄在时间1为11.8 ± 1.5岁，在时间7为23.7 ± 2.1岁。在第7时间点，32.4%（23/71）符合当前艾德的标准，另外8.5%（6/71）有亚阈值ED。艾德发作（完全综合征或低于阈值）时的平均年龄为22.6岁（95%CI 21.6-23.5），25岁时的累积发作概率为60%。从艾德发作到随后艾德缓解的平均时间为4.3年（95% CI 3.1-5.5），发作后6年缓解的累积概率为79%。缓解艾德和随后的复发之间的平均时间为6.5年（95%CI 4.4-8.6），和复发的累积概率为53%，6年后缓解.CONCLUSIONSIn这项纵向研究，ED是常见的和持久的，和新的发病艾德记录到成年。迫切需要对这一弱势群体的预防和治疗进行进一步研究。
OBJECTIVEGirls and women with type 1 diabetes are at increased risk for developing eating disorders (EDs), and these disorders are associated with serious diabetes-related medical complications. This study describes the longitudinal course of disturbed eating behavior (DEB) and EDs in a cohort with type 1 diabetes.RESEARCH DESIGN AND METHODSA total of 126 girls with type 1 diabetes receiving care for diabetes at The Hospital for Sick Children in Toronto participated in a series of seven interview-based assessments of ED behavior and psychopathology over a 14-year period, beginning in late childhood. Survival analysis was used.RESULTSMean age was 11.8 1.5 years at time 1 and 23.7 +/- 2.1 years at time 7. At time 7, 32.4% (23/71) met the criteria for a current ED, and an additional 8.5% (6/71) had a subthreshold ED. Mean age at ED onset (full syndrome or below the threshold) was 22.6 years (95% CI 21.6-23.5), and the cumulative probability of onset was 60% by age 25 years. The average time between onset of ED and subsequent ED remission was 4.3 years (95% CI 3.1-5.5), and the cumulative probability of remission was 79% by 6 years after onset. The average time between remission of ED and subsequent recurrence was 6.5 years (95% CI 4.4-8.6), and the cumulative probability of recurrence was 53% by 6 years after remission.CONCLUSIONSIn this longitudinal study, EDs were common and persistent, and new onset of ED was documented well into adulthood. Further research regarding prevention and treatment for this vulnerable group is urgently needed.