Probiotics in the prevention and treatment of gastrointestinal infections
Probiotics in the prevention and treatment of gastrointestinal infections
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DOI：
10.1016/j.gtc.2006.03.005
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发表时间：
2006-06-01
影响因子：
3.7
通讯作者：
Surawicz, Christina M.
中科院分区：
文献类型：
--
作者：
Huebner, Elizabeth S.;Surawicz, Christina M.
在过去的几十年里，对使用益生菌预防和治疗胃肠道感染的兴趣有所增加。对照试验支持益生菌在预防腹泻相关腹泻和治疗复发性梭菌相关疾病中的作用。在儿科人群中，对照试验显示了预防和治疗急性腹泻的疗效。一些研究表明乳酸杆菌对幽门螺杆菌有抑制作用，初步报告表明益生菌可能会减少胰腺炎的继发感染。评估其用于预防旅行者腹泻的研究产生了相互矛盾的结果。需要更多的试验来更好地确定益生菌在预防和治疗胃肠道疾病中的作用。
Interest in the use of probiotics; for the prevention and treatment of gastrointestinal infections has increased over the past few decades. Controlled trials support a role for probiotics in the prevention of antibiotic-associated diarrhea and in the treatment of recurrent Clostridium dffiicile-associated disease. In the pediatric population, controlled trials have shown efficacy in the prevention and treatment of acute diarrhea. Several studies have shown a suppressive effect of lactobacilli on Helicobacter pylori, and preliminary reports suggest that probiotics may decrease secondary infections in pancreatitis. Studies that evaluated their use for the prevention of traveler's diarrhea produced conflicting results. Additional trials are needed to define better the role of probiotics in the prevention and treatment of gastrointestinal diseases.