Point: alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma.
Point: alterations in airway smooth muscle phenotype do/do not cause airway hyperresponsiveness in asthma.
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DOI：
10.1152/japplphysiol.00483.2012
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发表时间：
2012-09
影响因子：
3.3
通讯作者：
S. Gunst;R. Panettieri
中科院分区：
文献类型：
--
作者：
S. Gunst;R. Panettieri
#### Summary. Airway hyperresponsiveness and obstruction are cardinal features of asthma. Compelling evidence now suggests that the key features of asthma in part are due to intrinsic differences in airway smooth muscle (ASM) function. Inflammatory mediators alter ASM phenotype, which directly
