Dehydrogenative Silylation of Alkenes for the Synthesis of Substituted Allylsilanes by Photoredox, Hydrogen-Atom Transfer, and Cobalt Catalysis
Dehydrogenative Silylation of Alkenes for the Synthesis of Substituted Allylsilanes by Photoredox, Hydrogen-Atom Transfer, and Cobalt Catalysis
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通过光氧化还原、氢原子转移和钴催化进行烯烃脱氢硅烷化合成取代烯丙基硅烷
DOI：
10.1002/anie.201904707
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Xu Peng Fei
中科院分区：
文献类型：
--
作者：
Yu Wan Lei;Luo Yong Chun;Yan Lei;Liu Dan;Wang Zhu Yin;Xu Peng Fei
发展了一种将光氧化还原催化、氢原子转移和质子还原催化相结合的协同催化方法，用于烯烃的双硅烷化反应。通过这种方法，在非常温和的反应条件下，不使用氧化剂，已经实现了一个高度简洁的路线取代烯丙基硅烷。这种转化具有良好的优异的产率，操作简单，和高原子经济性。在对照实验的基础上，提出了一种可能的反应机理。
A synergistic catalytic method combining photoredox catalysis, hydrogen‐atom transfer, and proton‐reduction catalysis for the dehydrogenative silylation of alkenes was developed. With this approach, a highly concise route to substituted allylsilanes has been achieved under very mild reaction conditions without using oxidants. This transformation features good to excellent yields, operational simplicity, and high atom economy. Based on control experiments, a possible reaction mechanism is proposed.