The development of the olfactory nerve in man
The development of the olfactory nerve in man
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DOI：
10.1002/cne.900750202
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发表时间：
1941-10-01
影响因子：
2.5
通讯作者：
Pearson, AA
中科院分区：
文献类型：
--
作者：
Pearson, AA
嗅神经的原基是由纤维的生长和细胞向大脑的迁移形成的。这些神经束形成一束，斜向上伸展到前脑的腹侧壁。这个神经束构成了胚胎的嗅神经。在嗅神经最初附着于前脑时，没有嗅球的迹象。在嗅神经与大脑的连接处，很快就会出现一个轻微的突起。大脑的突出部分是嗅球的原基。球发育为前脑壁的外翻。嗅球扩大，胚胎嗅神经伸展成一层纤维，部分覆盖在嗅球表面。在早期发育中，嗅球向下并略微向后。随着发展的继续，它逐渐向前发展。
The anlage of the olfactory nerve is formed by the growth of fibers and the migration of cells toward the brain. These form a bundle which stretches obliquely upward toward the ventral wall of the forebrain. This bundle constitutes the embryonic olfactory nerve. At the time of the initial attachment of the olfactory nerve to the forebrain there is no indication of an olfactory bulb. A slight protrusion soon develops in the region of the attachment of the olfactory nerve to the brain. This protrusion of the brain is the anlage of the olfactory bulb. The bulb develops as an evagination of the wall of the forebrain. The olfactory bulb enlarges and the embryonic olfactory nerve spreads out into a layer of fibers which partially covers the surface of the bulb. In its early development the olfactory bulb is directed downward and slightly backward. It is gradually directed forward as development continues.