Thickness of the subchondral mineralised tissue zone (SMZ) in normal male and female and pathological human patellae
Thickness of the subchondral mineralised tissue zone (SMZ) in normal male and female and pathological human patellae
复制标题
DOI：
10.1046/j.1469-7580.1998.19210081.x
复制
发表时间：
1998-01-01
影响因子：
2.4
通讯作者：
Putz, R
中科院分区：
文献类型：
--
作者：
Eckstein, F;Milz, S;Putz, R
本文的目的是分析性别差异的厚度的subchoneliummineralised组织区（SMZ），并找出是否SMZ厚度的系统性变化与自然发生的，非全层软骨病变的人髌骨。在32个甲基丙烯酸甲酯包埋的标本（16个正常，8个局灶性内侧，8个与外侧病变）SMZ厚度测定，使用双目宏观镜和图像分析系统。在每种情况下，在整个关节表面重建厚度分布。男性SMZ最大厚度和平均厚度均显著高于女性（P < 0.01）。正常髌骨和外侧损伤髌骨外侧厚度明显大于内侧（P < 0.05），内侧损伤髌骨外侧厚度大于内侧（P < 0.05）。内侧损伤的髌骨总平均值和外侧平均值显著低于外侧损伤的髌骨（P < 0.05）。内侧病变下方SMZ厚度低于外侧病变下方，但局部厚度始终在正常标本的范围内。结论：髌骨SMZ厚度存在性别差异。然而，自然发生的软骨病变似乎与SMZ厚度的局部变化无关，但它们可能与关节表面内改变的区域分布模式有关。
The objective of this paper was to analyse sex differences of the thickness of the subchondral mineralised tissue zone (SMZ), and to find out whether systematic changes of SMZ thickness are associated with naturally occurring, non-full-thickness cartilage lesions of human patellae. In 32 methyl-methacrylate-embedded specimens (16 normal, 8 with focal medial, and 8 with lateral lesions) the SMZ thickness was determined, using a binocular macroscope and an image analysing system. In each case, the thickness distribution was reconstructed throughout the entire joint surface. The maximal and mean SMZ thicknesses were significantly higher in males than in females (P < 0.01). In normal patellae and those with lateral lesions, the thickness was significantly thicker laterally than medially (P < 0.05), but it was not in specimens with medial damage. Patellae with medial damage exhibited a significantly lower total mean and lateral mean (P < 0.05). A lower SMZ thickness was found directly beneath medial lesions than beneath lateral ones, but the local thickness was always in the range of that observed in normal specimens. We conclude that differences of patellar SMZ thickness exist between males and females. Naturally occurring cartilage lesions appear, however, not to be associated with local changes of SMZ thickness, but they may be associated with an altered regional distribution pattern within the joint surface.