Higher patient perceived side effects related to higher daily doses of inhaled corticosteroids in the community: A cross-sectional analysis
Higher patient perceived side effects related to higher daily doses of inhaled corticosteroids in the community: A cross-sectional analysis
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DOI：
10.1016/j.rmed.2005.11.029
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发表时间：
2006-08-01
影响因子：
4.3
通讯作者：
van der Molen, Thys
中科院分区：
文献类型：
--
作者：
Foster, Juliet M.;Aucott, Lorna;van der Molen, Thys
一般社区患者吸入皮质类固醇（ICS）副作用的范围和程度可能被低估。目的：确定社区患者感知的ICS副作用，并通过使用自我报告问卷，测量其强度，患病率及其与每日药物剂量的关系。方法：进行焦点小组和深入访谈，以确定患者与使用ICS相关的副作用。在一项国际多中心横断面调查中，来自社区药房的395名吸入器使用者（平均年龄50岁，53%为女性）分为4个每日剂量组（β（2）-激动剂不含ICS n = 66，丙酸倍氯米松（BDP）等效ICS低剂量800 μ g，n = 69），报告了他们在7分Likert量表上受这些副作用的影响程度。
The range and extent of inhaled corticosteroid (ICS) side effects experienced by patients in the general community are likely to be underestimated. Aims: To identify the side effects of ICS perceived by patients in the community and, through the use of a self-report questionnaire, measure their intensity, prevalence and relationship with daily medication dose. Methods: Focus groups and in-depth interviews were conducted to identify side effects that patients associated with their use of ICS. In an international multicentre cross-sectional survey, 395 inhaler users from community pharmacy (mean age 50, 53% female), divided into 4 daily dosage groups (beta(2)-agonist without ICS n = 66, beclometasone dipropionate (BDP) equivalent ICS low dose 800 mu g, n = 69) reported how much they were affected by these side effects on a 7-point Likert scale.