A Personal Respirator to Improve Protection for Healthcare Workers Treating COVID-19 (PeRSo).
A Personal Respirator to Improve Protection for Healthcare Workers Treating COVID-19 (PeRSo).
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DOI：
10.3389/fmedt.2021.664259
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发表时间：
2021
影响因子：
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通讯作者：
Morgan H
中科院分区：
文献类型：
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作者：
Elkington PT;Dickinson AS;Mavrogordato MN;Spencer DC;Gillams RJ;De Grazia A;Rosini S;Garay-Baquero DJ;Diment LE;Mahobia N;Mant A;Baynham T;Morgan H
引言：新型冠状病毒（SARS - CoV - 2）感染是一场全球性大流行。就全球库存、供应物流和适用性而言，用于保护医护人员的个人防护装备（PPE）一直是一个反复出现的难题。在一些情况下，治疗新冠肺炎病例的医护人员中约有20%被感染，这导致在疫情高峰期医护人员缺勤，在某些情况下还会导致死亡。
方法：为了解决个人防护装备的不足，我们开发了一种简易的动力送风过滤式呼吸器，它由价格低廉且广泛可得的部件组成。该原型的设计旨在将制造复杂性降至最低，以便在资源匮乏的环境中只需稍加修改就能开发出衍生版本。
结果：“南安普顿个人呼吸器”（PeRSo）通过电池供电的风扇 - 过滤器组件将经高效空气过滤器（HEPA）过滤的空气输送到一个带有透明面罩的轻质头罩中，该头罩可舒适佩戴数小时。验证测试表明，该原型可去除微生物，在正常使用中避免二氧化碳过度积聚，并且通过了广泛用于评估标准N95/FFP2和N99/FFP3口罩的密合性测试方案。医生和护士的反馈表明，与标准的FFP2和FFP3口罩相比，他们更喜欢PeRSo原型，因为它更舒适，减少了反复更换个人防护装备的时间和风险。患者表示，由于整个面部可见，沟通效果更好，也更安心。
结论：快速扩大低成本生产的动力送风过滤式呼吸器的生产规模，使其在生产国获得监管批准，可在新冠肺炎疫情期间保护医护人员免受感染，并改善医疗服务。
Introduction: SARS-CoV-2 infection is a global pandemic. Personal Protective Equipment (PPE) to protect healthcare workers has been a recurrent challenge in terms of global stocks, supply logistics and suitability. In some settings, around 20% of healthcare workers treating COVID-19 cases have become infected, which leads to staff absence at peaks of the pandemic, and in some cases mortality. Methods: To address shortcomings in PPE, we developed a simple powered air purifying respirator, made from inexpensive and widely available components. The prototype was designed to minimize manufacturing complexity so that derivative versions could be developed in low resource settings with minor modification. Results: The “Personal Respirator – Southampton” (PeRSo) delivers High-Efficiency Particulate Air (HEPA) filtered air from a battery powered fan-filter assembly into a lightweight hood with a clear visor that can be comfortably worn for several hours. Validation testing demonstrates that the prototype removes microbes, avoids excessive CO2 build-up in normal use, and passes fit test protocols widely used to evaluate standard N95/FFP2 and N99/FFP3 face masks. Feedback from doctors and nurses indicate the PeRSo prototype was preferred to standard FFP2 and FFP3 masks, being more comfortable and reducing the time and risk of recurrently changing PPE. Patients report better communication and reassurance as the entire face is visible. Conclusion: Rapid upscale of production of cheaply produced powered air purifying respirators, designed to achieve regulatory approval in the country of production, could protect healthcare workers from infection and improve healthcare delivery during the COVID-19 pandemic.