Risk Factors for Heart Failure: A Population-Based Case-Control Study
Risk Factors for Heart Failure: A Population-Based Case-Control Study
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DOI：
10.1016/j.amjmed.2009.04.022
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发表时间：
2009-11-01
影响因子：
5.9
通讯作者：
Roger, Veronique L.
中科院分区：
文献类型：
--
作者：
Dunlay, Shannon M.;Weston, Susan A.;Roger, Veronique L.
背景：危险因素对心力衰竭发生的相对作用仍有争议。此外，还不清楚这些贡献是否随着时间的推移而变化或因性别而异。很少有基于人群的研究已经进行。我们的目的是估计人口归因风险（PAR）与心脏衰竭的关键危险因素在community.METHODS：1979年至2002年，962事件在奥姆斯特德县心力衰竭病例年龄和性别匹配的人口为基础的控制使用罗切斯特流行病学项目资源。我们确定了危险因素（冠心病、高血压、糖尿病、肥胖和吸烟）的频率、优势比和每种心力衰竭危险因素的PAR。
BACKGROUND: The relative contribution of risk factors to the development of heart failure remains controversial. Further, whether these contributions have changed over time or differ by sex is unclear. Few population-based studies have been performed. We aimed to estimate the population attributable risk (PAR) associated with key risk factors for heart failure in the community.METHODS: Between 1979 and 2002, 962 incident heart failure cases in Olmsted County were age and sex-matched to population-based controls using Rochester Epidemiology Project resources. We determined the frequency of risk factors (coronary heart disease, hypertension, diabetes mellitus, obesity, and smoking), odds ratios, and PAR of each risk factor for heart failure.RESULTS: The mean number of risk factors for heart failure per case was 1.9 +/- 1.1 and increased over time (P