SUGAR CLEARANCE FROM SALIVA AND INTRA-ORAL SPACES
SUGAR CLEARANCE FROM SALIVA AND INTRA-ORAL SPACES
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DOI：
10.1177/00220345850640030301
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发表时间：
1985-01-01
影响因子：
7.6
通讯作者：
ATTARZADEH, F
中科院分区：
文献类型：
--
作者：
GOULET, D;BRUDEVOLD, F;ATTARZADEH, F
从唾液中的葡萄糖的清除率与从位于口腔内器具中的空间中的葡萄糖的清除率进行比较。间隙（N = 8）的形状和大小类似于后牙间隙，它们可以用微量注射器取样，而无需将器具从口腔中取出。受试者（N = 5）用5、10或25%葡萄糖溶液漱口。以标准间隔从一对空间和唾液中获得样品，并分析其葡萄糖。葡萄糖从间隙中的清除速率始终比从大量唾液中的清除速率慢，如间隙的较高浓度和较长清除时间所示。清除率曲线形状相似，当绘制浓度的对数与时间的关系图时，清除率曲线呈直线。间隙的清除率似乎是个体的特征，唾液清除率也是如此。[已知溶解在唾液中的糖是致龋细菌的底物。]。
The clearance of glucose from saliva was compared with that from spaces located in an intra-oral appliance. The spaces (N = 8) were similar in shape and size to posterior interdental spaces, and they could be sampled with a microsyringe without removing the appliance from the mouth. The subjects (N = 5) rinsed their mouths with solutions of 5, 10, or 25% glucose. Samples were obtained from a pair of spaces and from saliva at standard intervals, and they were analyzed for glucose. The rate of glucose clearance was consistently slower from the spaces than from bulk saliva, as shown by higher concentrations and longer clearance times for the spaces. The clearance curves were similar in shape, and were rectilinear when the logarithms of the concentrations were plotted against time. The rate of clearance from the spaces appears to be characteristic for an individual, as was also true of salivary clearance. [Sugar dissolved in saliva is known to be a substrate for cariogenic bacteria.].