VsN, a Reliability-index of Shear-wave Measurement in Sonoelastography, Is Useful for the Diagnosis of Thyroid Tumor Malignancy
VsN, a Reliability-index of Shear-wave Measurement in Sonoelastography, Is Useful for the Diagnosis of Thyroid Tumor Malignancy
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DOI：
10.21873/invivo.12700
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发表时间：
2022-01-01
期刊：
影响因子：
2.3
通讯作者：
Sugitani, Iwao
中科院分区：
文献类型：
--
作者：
Jikuzono, Tomoo;Ishibashi, Osamu;Sugitani, Iwao
背景/目的：剪切波测量（SWM）是一种新的弹性成像模式，其量化剪切波速度（Vs）和净有效剪切波速度（VsN）的百分比。本研究探讨这些参数是否可用于区分恶性和良性甲状腺肿瘤。患者和方法：SWM研究纳入了111例（133个结节）接受甲状腺手术的患者。总体上，61个结节被诊断为良性，72个结节被诊断为恶性，其中68个结节被诊断为甲状腺乳头状癌（PTC），4个结节被诊断为甲状腺滤泡状癌（FTC）。结果：术前SWM显示，与良性结节相比，PTC的Vs明显较高，VsN明显较低。FTC的VsN明显低于滤泡性腺瘤。多因素分析显示VsN与结节恶性程度显著相关。结论：SWM参数，尤其是VsN，可无创性鉴别甲状腺结节的良恶性。
Background/Aim: Shear wave measurement (SWM) is a new elastography modality that quantifies the shear wave velocity (Vs) and the percentage of the net effective shear wave velocity (VsN). This study examined whether these parameters could be used to differentiate between malignant and benign thyroid tumors. Patients and Methods: The study of SWM enrolled 111 patients (133 nodules) who underwent thyroid surgery. Overall, 61 nodules were diagnosed as benign and 72 as malignant, of which 68 nodules were diagnosed as papillary thyroid carcinoma (PTC) and 4 as follicular thyroid carcinoma (FTC). Results: A preoperative SWM revealed that Vs was significantly higher and VsN significantly lower in the PTC compared to the benign nodules. The VsN of FTC was significantly lower than that of follicular adenoma. Multivariate analysis revealed that VsN significantly correlated with nodule malignancy. Conclusion: SWM parameters, especially VsN, can potentially differentiate between benign and malignant thyroid nodules non invasively.