Assessment of antibiotic prescribing behavior of consultants of different localities of Pakistan
Assessment of antibiotic prescribing behavior of consultants of different localities of Pakistan
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DOI：
10.5897/ajpp11.051
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发表时间：
2011-05-01
影响因子：
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通讯作者：
Hussain, Shahzad
中科院分区：
文献类型：
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作者：
Riaz, Humayun;Malik, Farnaz;Hussain, Shahzad
研究的目的是评估巴基斯坦对抗疗法卫生部门顾问的模式和做法，特别是抗菌剂，以评估问题的严重程度并提出纠正措施。在巴基斯坦各城市进行了一项横断面调查，该调查是根据世卫组织制定的，迄今已在12个发展中国家实施。收集并分析了197名会诊医师4923张处方。配发药品480142种；各学科处方平均用药数为3.13 +/- 1.5。内科抗生素使用次数占总抗生素使用次数的20.17%，而眼科无注射类抗生素使用次数。23.79%的处方费用低于100卢比，4.9%的处方费用高于500卢比。处方药物的治疗类别以抗菌药物占14.6%，其次是心血管或肾脏药物占12.5%。患者的年龄、疾病的严重程度、社会经济状况、以往治疗类似患者的经验是决定药物选择的重要因素。大多数设施都没有电子数据分析。大约80%的药物是用品牌开的。从基本清单中开出的药物约占30%。只有18%的医生认为病人流失给其他医生是前三大因素之一。患者的年龄、疾病的严重程度、社会经济因素是决定药物选择的重要因素。像许多发展中国家一样，巴基斯坦的处方和配药做法是不适当和不合理的。提出了管理和监管干预措施，以改善药物的合理使用。
The objective of study was to evaluate the pattern and practice of consultants especially antimicrobials in the allopathic health sector in Pakistan to assess the magnitude of the problem and suggesting corrective measures. A cross-sectional survey in various cities of Pakistan was conducted which was developed in line with WHO and has so far been implemented in 12 developing countries. A total of 4923 prescriptions of 197 consultants were collected and analyzed. Drugs dispensed were 480142; average number of drugs per prescription for all disciplines was 3.13 +/- 1.5. The number of encounters with antibiotics in medicine department was 20.17% of the total antibiotic while ophthalmology had no encounter with injectables. Cost of 23.79% of prescriptions was below Rs.100 and 4.9% above 500 rupees. Therapeutic categories of the drugs prescribed were 14.6% antimicrobial followed by 12.5% cardiovascular or renal drugs. The age of the patient, severity of disease, socio-economic status, previous experience of treating similar patients were important factors that determined choice of drugs. EDL was not available in most of the facilities. Around 80% drugs were prescribed by brand name. The drugs prescribed from the essential list were around 30%. Concern of losing patients to others practitioners was considered among the top three factors by only 18% of providers. Age of the patient, severity of disease, socio-economic factors were important factors that determined choice of drugs. Prescribing and dispensing practices are inappropriate and irrational in Pakistan like many developing countries. Managerial and regulatory interventions are proposed to improve the rational use of drugs.