Murine SLE models and autoimmune disease.
Murine SLE models and autoimmune disease.
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小鼠 SLE 模型和自身免疫性疾病。
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
F. Dixon
中科院分区：
文献类型：
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作者：
F. Dixon
现在存在三种不同品系的“狼疮小鼠”。对这些动物的研究不仅为系统性红斑狼疮本身提供了见解，而且为一般的自身免疫性疾病提供了见解，或许还为类风湿性关节炎、冠状动脉疾病和心肌梗塞提供了见解。对于所有菌株，都有可能确定导致早期和更严重疾病表现的特定加速因素。
There are now three distinct strains of “lupus mice.” Studies of these animals have provided insights not only into SLE itself but into autoimmune disease in general, and perhaps also into rheumatoid arthritis, coronary artery disease, and myocardial infarction. With all strains, it has been possible to identify specific accelerating factors that appear to contribute to early and more severe disease manifestations.